Browsing by Author "Erdogan, Mumin Alper"

Induction of Behavioral and Histological Alterations in Rats by Chronic Consuming of Artificial Sweeteners: A Comparative Study

Erdogan, Mumin Alper; Erbas, Oytun; Khalilnezhad, Asghar; Gurkan, Fulya Tuzcu; Yigitturk, Gurkan; Taskiran, Dilek (WILEY-BLACKWELL, 2016)

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Levodropropizine suppresses seizure activity in rats with pentylenetetrazol-induced epilepsy

Erdogan, Mumin Alper; Yusuf, Dimas; Erdogan, Arife; Erbas, Oytun (ELSEVIER SCIENCE BV, 2019)

Background: Millions of individuals worldwide suffer from epilepsy, and up to 25% of patients have seizures that are resistant to currently available antiepileptic drugs. Hence, there continues to be a need for more seizure ...

N-acetyl cysteine: A new look at its effect on PTZ-induced convulsions

Egilmez, Cansu Bilister; Pazarlar, Burcu Azak; Erdogan, Mumin Alper; Erbas, Oytun (Elsevier, 2023)

Introduction/Aim: Epilepsy is widely investigated as a common neurological disease requiring pharmacologically effective agents. N-acetyl cysteine (NAC), has become a remarkable molecule with its role in both antioxidant ...

Neurobehavioral effects of long-term maternal fructose intake in rat offspring

Erbas, Oytun; Erdogan, Mumin Alper; Khalilnezhad, Asghar; Gurkan, Fulya Tuzcu; Yigitturk, Gurkan; Meral, Ayfer; Taskiran, Dilek (PERGAMON-ELSEVIER SCIENCE LTD, 2018)

Background: Previous studies have indicated an association between maternal metabolic conditions and general developmental disturbances of the offspring. Objective: We aimed to investigate the influence of long-term maternal ...

Neuroprotective effect of dexpanthenol on rotenone-induced Parkinson's disease model in rats

Egilmez, Cansu Bilister; Pazarlar, Burcu Azak; Erdogan, Mumin Alper; Erbas, Oytun (Elsevier Ireland Ltd, 2024)

Parkinson's disease (PD) is the second most common and progressive neurodegenerative disease. This experimental study was designed to investigate the neuroprotective effects of dexpanthenol on antioxidant and antiinflammatory ...

Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats

Erdogan, Mumin Alper; Yigitturk, Gurkan; Erbas, Oytun; Taskiran, Dilek (Taylor & Francis Ltd, 2021)

Aim Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ...

The potential effects of anticonvulsant drugs on neuropeptides and neurotrophins in pentylenetetrazol kindled seizures in the rat

Tekgul, Hasan; Simsek, Erdem; Erdogan, Mumin Alper; Yigitturk, Gurkan; Erbas, Oytun; Taskiran, Dilek (Taylor & Francis Ltd, 2020)

Purpose: Neuropeptides and neurotrophic factors are thought to be involved in epileptogenesis. This study aims to investigate the potential effects of anticonvulsant drugs on neuropeptides (galanin and neuropeptide Y) and ...

Prenatal Exposure to COVID-19 mRNA Vaccine BNT162b2 Induces Autism-Like Behaviors in Male Neonatal Rats: Insights into WNT and BDNF Signaling Perturbations

Erdogan, Mumin Alper; Gurbuz, Orkun; Bozkurt, Mehmet Fatih; Erbas, Oytun (Springer/Plenum Publishers, 2024)

The COVID-19 pandemic catalyzed the swift development and distribution of mRNA vaccines, including BNT162b2, to address the disease. Concerns have arisen about the potential neurodevelopmental implications of these vaccines, ...

Prenatal SARS-CoV-2 Spike Protein Exposure Induces Autism-Like Neurobehavioral Changes in Male Neonatal Rats

Erdogan, Mumin Alper; Turk, Miray; Doganay, Gizem Dinler; Sever, Ibrahim Halil; Ozkul, Bahattin; Sogut, Ibrahim; Eroglu, Ebru (Springer, 2023)

Recent research on placental, embryo, and brain organoids suggests that the COVID-19 virus may potentially affect embryonic organs, including the brain. Given the established link between SARS-CoV-2 spike protein and ...

Protective effect of dapagliflozin on colistin-induced renal toxicity

Bora, Ejder Saylav; Erdogan, Mumin Alper; Meral, Ayfer; Karakaya, Zeynep; Erbas, Oytun (Mre Press, 2021)

Objectives: Multiple-drug resistance to Gram-negative bacteria has increased significantly in recent years. Colistin is increasingly used as a last line of defense against these bacteria. However, colistin has been associated ...

Protective Effect of Polyethylene Glycol (PEG) 3350 on a Cisplatin-Induced Rat Model of Neuropathy

Gonullu, Edip; Dagistan, Gozde; Erdogan, Mumin Alper; Erbas, Oytun (Asian Network Scientific Information-Ansinet, 2022)

Background and Objective: Peripheral neuropathy is the most important side effect, leading to a decrease in the dose of cisplatin or its complete cessation in the early period. For this purpose, the study aimed to investigate ...

The Protective Effects of Carvedilol on Diabetic Nephropathy in A Streptozotocin-Induced Diabetic Rat Model

Erdogan, Mumin Alper; Yigitturk, Gurkan; Erbas, Oytun (Wiley, 2019)

[No abstract available]

Protective Effects of Ibudilast Against Cisplatin-Induced Hepatotoxicity and Nephrotoxicity Mediated by Prostacyclin Enhancement

Ozkul, Ozlem; Ozkul, Bahattin; Erdogan, Mumin Alper; Erbas, Oytun (Asian Network Scientific Information-Ansinet, 2023)

Background and Objective: Cisplatin, a prevalent chemotherapy drug, presents hepatotoxic and nephrotoxic side effects, this study explores ibudilast's potential protective effects against such damage via prostacyclin ...