Yazar "Yigitturk, Gurkan" için listeleme
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Neurobehavioral effects of long-term maternal fructose intake in rat offspring
Erbas, Oytun; Erdogan, Mumin Alper; Khalilnezhad, Asghar; Gurkan, Fulya Tuzcu; Yigitturk, Gurkan; Meral, Ayfer; Taskiran, Dilek (PERGAMON-ELSEVIER SCIENCE LTD, 2018)Background: Previous studies have indicated an association between maternal metabolic conditions and general developmental disturbances of the offspring. Objective: We aimed to investigate the influence of long-term maternal ... -
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats
Erdogan, Mumin Alper; Yigitturk, Gurkan; Erbas, Oytun; Taskiran, Dilek (Taylor & Francis Ltd, 2021)Aim Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ... -
Neuroprotective effects of erythropoietin on Alzheimer's dementia model in rats
Cevik, Betul; Solmaz, Volkan; Yigitturk, Gurkan; Cavusoglu, Turker; Peker, Gonul; Erbas, Oytun (WROCLAW MEDICAL UNIV, 2017)Background. Although Alzheimer's disease (AD) is the most common age-related neurodegenerative disease and characterized by memory impairment, only symptomatic treatments are available. Objectives. Because recombinant human ... -
Neuroprotective effects of octreotide on diabetic neuropathy in rats
Solmaz, Volkan; Cinar, Bilge Piri; Yigitturk, Gurkan; Ozlece, Hatice Kose; Eroglu, Huseyin Avni; Tekatas, Aslan; Taskiran, Dilek (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017)The purpose of the present study is to investigate the possible healing effects of octreotide (OCT) on motor performance, electrophysiological and histopathological findings of diabetic neuropathy in a rat model of diabetes ... -
Octreotide protects ovary against ischemia-reperfusion injury in rats: Evaluation of histological and biochemical parameters
Yildirim, Nuri; Yigitturk, Gurkan; Yildirim, Alkim Gulsah Sahingoz; Akdemir, Ali; Ilgen, Orkun; Yeniel, Ozgur; Erbas, Oytun (WILEY-BLACKWELL, 2015)AimThis study investigated the efficacy of octreotide for prevention of ischemia-reperfusion injury in rat ovary. MethodsThirty-two adult female rats were included. Rats were divided into five groups: in the sham group, ... -
Oxytocin and cabergoline alleviate ovarian hyperstimulation syndrome (OHSS) by suppressing vascular endothelial growth factor (VEGF) in an experimental model
Hortu, Ismet; Karadadas, Elif; Ozceltik, Gokay; Tavmergen, Erol; Tavmergen Goker, Ege Nazan; Yigitturk, Gurkan; Erbas, OytunPurpose Ovarian hyperstimulation syndrome (OHSS) is a life-threatening complication of ovarian stimulation in reproductive medicine. Here, we aimed to investigate the role of oxytocin (OT) and cabergoline in the prevention ... -
The potential effects of anticonvulsant drugs on neuropeptides and neurotrophins in pentylenetetrazol kindled seizures in the rat
Tekgul, Hasan; Simsek, Erdem; Erdogan, Mumin Alper; Yigitturk, Gurkan; Erbas, Oytun; Taskiran, Dilek (Taylor & Francis Ltd, 2020)Purpose: Neuropeptides and neurotrophic factors are thought to be involved in epileptogenesis. This study aims to investigate the potential effects of anticonvulsant drugs on neuropeptides (galanin and neuropeptide Y) and ... -
The protective effect of Gingko biloba in a rat model of ovarian ischemia/reperfusion injury: Improvement in histological and biochemical parameters
Yildirim, Nuri; Simsek, Deniz; Kose, Semir; Yildirim, Alkim Gulsah Sahingoz; Guven, Cagri; Yigitturk, Gurkan; Erbas, Oytun (WROCLAW MEDICAL UNIV, 2018)Background. Ovarian torsion is one of the most common gynecological emergencies, which especially affects women of reproductive age. Objectives. We aimed to evaluate the effect of Ginkgo biloba (GB) supplementation in ... -
Protective effect of oxytocin on a methotrexate-induced ovarian toxicity model
Hortu, Ismet; Ozceltik, Gokay; Ergenoglu, Ahmet Mete; Yigitturk, Gurkan; Atasoy, Ozum; Erbas, Oytun (Springer Heidelberg, 2020)Purpose Although cancer predominantly affects people at older ages, a substantial number of patients, like breast cancer patients, are diagnosed before they have completed their families or even before giving birth. ... -
The Protective Effects of Carvedilol on Diabetic Nephropathy in A Streptozotocin-Induced Diabetic Rat Model
Erdogan, Mumin Alper; Yigitturk, Gurkan; Erbas, Oytun (Wiley, 2019)[No abstract available] -
The Restorative Effect of Gallic Acid on the Experimental Sciatic Nerve Damage Model
Gurkan, Gokhan; Erdogan, Mumin Alper; Yigitturk, Gurkan; Erbas, Oytun (Korean Neurosurgical Soc, 2021)Objective : Peripheral nerve injuries occur mostly as a result of mechanical trauma. Due to the microvascular deterioration in peripheral nerve damage, it becomes challenging to remove free oxygen radicals. Gallic acid is ... -
The Role of Ankaferd Blood Stopper and Oxytocin as Potential Therapeutic Agents in Endometriosis: A Rat Model
Hortu, Ismet; Ozceltik, Gokay; Karadadas, Elif; Erbas, Oytun; Yigitturk, Gurkan; Ulukus, Murat (Springer, 2020)To evaluate the potential effect of Ankaferd Blood Stopper (ABS) and oxytocin (OT) in an experimental endometriosis model, 18 female Sprague Dawley rats were used in this study. the animals were divided randomly into three ... -
Silymarin ameliorates uterine and ovarian damage in streptozotocin induced diabetic rat model
Yildirim, Nuri; Kose, Semir; Yildirim, AlkimGulsahSahingoz; Sahin, Cagdas; Yigitturk, Gurkan; Yavasoglu, Altug; Erbas, Oytun (NATL INST SCIENCE COMMUNICATION-NISCAIR, 2018)Diabetes is a systemic disease that affects microvasculature in almost all organs. Uterus and the ovaries may also be a target for diabetes. We investigated effects of diabetes on the uterus and the ovaries and the role ... -
Tadalafil attenuates ischemic damage as well as reperfusion injury in the rat ovary
Sahin, Cagdas; Yildirim, Nuri; Akdemir, Ali; Ozsener, Serdar; Yigitturk, Gurkan; Erbas, Oytun (Galenos Yayincilik, 2020)Objective: Tadalafil is a selective phosphodiesterase type-5 inhibitor with a long half-life. It has a dual function in ischaemic and re-perfused tissues, i.e. vasodilatation and anti-oxidant effects. These features of ... -
The Protective Role of Resveratrol on Diabetic Cardiomyopathy
Canbolat, Ismail Polat; Cavusoglu, Turker; Yigitturk, Gurkan; Ates, Utku; Erbas, Oytun (EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2017)… -
Therapeutic effect of adenosine on experimentally induced acute ulcerative colitis model in rats
Ercan, Gulcin; Yigitturk, Gurkan; Erbas, Oytun (Acta Cirurgica Brasileira, 2019)Purpose: To examine the therapeutic effect of external adenosine on an acetic acid-induced acute ulcerative colitis model in rats. Methods: Thirty male mature rats were divided into three groups as control, acute colitis ... -
Therapeutic effects of vitamin D on acetic acid-induced colitis in rats
Bademci, Refik; Erdogan, Mumin Alper; Kara, Ali Yucel; Yigitturk, Gurkan; Erbas, Oytun (Acta Cirurgica Brasileira, 2020)Purpose: To analyze the effect of calcitriol treatment on acute colitis in an experimental rat model. Methods: A total of 24 adult Sprague Dawley albino rats were randomly separated into 3 equal groups: control group (n:8), ...