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herg1b Expression as a Potential Specific Marker in Pediatric Acute Myeloid Leukemia Patients with HERG 897K/K Genotype
Erdem, Merve; Tekiner, Tugce Ayca; Fejzullahu, Arta; Akan, Gokce; Anak, Sema; Saribeyoglu, Ebru Tugrul; Atalar, Fatmahan (TAYLOR & FRANCIS INC, 2015)Human ether-a-go-go related gene (herg) encoding HERG K+ channel has been demonstrated in many previous studies with its association to cell cycle progression and growth in tumor cells. The upregulated expression of HERG ... -
Mediastinal adipose tissue expresses a pathogenic profile of 11 beta-hydroxysteroid dehydrogenase Type 1, glucocorticoid receptor, and CD68 in patients with coronary artery disease
Atalar, Fatmahan; Gormez, Selcuk; Caynak, Baris; Akan, Gokce; Tanriverdi, Gamze; Bilgic-Gazioglu, Sema; Yazici, Zeliha (ELSEVIER SCIENCE INC, 2013)Objective: Cardiac visceral fat is accepted to be a new marker for cardiometabolic risk due to its association with increased cardiovascular risk factors. This study aimed to compare the expression of 11 beta hydroxysteroid ... -
Relationships between visceral/subcutaneous adipose tissue FABP4 expression and coronary atherosclerosis in patients with metabolic syndrome
Gormez, Selcuk; Erdim, Refik; Akan, Gokce; Caynak, Baris; Duran, Cihan; Gunay, Demet; Atalar, Fatmahan (Elsevier Science Inc, 2020)Background: Cytoplasmic fatty acid-binding proteins facilitate the transport of lipids to specific compartments in cells. Fatty acid-binding protein 4 (FABP4), also known as aP2 or A-FABP, plays a key role in the development ... -
The role of mediastinal adipose tissue 11 beta-hydroxysteroid d ehydrogenase type 1 and glucocorticoid expression in the development of coronary atherosclerosis in obese patients with ischemic heart disease
Atalar, Fatmahan; Gormez, Selcuk; Caynak, Baris; Akan, Gokce; Tanriverdi, Gamze; Bilgic-Gazioglu, Sema; Yazici, Zeliha (BMC, 2012)Background: Visceral fat deposition and its associated atherogenic complications are mediated by glucocorticoids. Cardiac visceral fat comprises mediastinal adipose tissue (MAT) and epicardial adipose tissue (EAT), and MAT ...