Yazar "Cevik, Mehtap" için listeleme
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The effects of CYP2C9 and VKORC1 gene polymorphisms on warfarin maintenance dose in Turkish cardiac patients
Akdeniz, Cansu Selcan; Cevik, Mehtap; Canbolat, Ismail Polat; Yurdakul, Selen; Cagatay, Penbe; Ciftci, Cavlan; Karaalp, Atila (Future Medicine Ltd, 2020)Aim: Our aim was to examine the effect of CYP2C9 and VKORC1 polymorphisms on warfarin dose requirements in Turkish patients. Materials & methods: 24 warfarin prescribed patients were included and analyzed for eight VKORC1 ... -
The effects of SNAI1 rs6125849 gene polymorphism on metastasis and survival in colorectal cancer: Preliminary results from Turkish subjects
Cevik, Mehtap; Namal, Esat; Sener, Nur Dinc; Koksal, Ulkuhan Iner; Deliorman, Gokce; Ciftci, Cavlan; Susleyici, Belgin (Elsevier, 2021)Background: Since metastasis is one of the leading causes of high mortality in colorectal cancer, uncovering the molecular mechanisms underlying metastatic process has become important to find new treatment approaches. ... -
Investigation of DPYD, MTHFR and TYMS polymorphisms on 5-fluorouracil related toxicities in colorectal cancer
Cevik, Mehtap; Namal, Esat; Sener, Nur Dinc; Koksal, Ulkuhan Iner; Cagatay, Penbe; Deliorman, Gokce; Susleyici, Belgin (Future Medicine Ltd, 2022)Aim: To investigate the association of DPYD, MTHFR and TYMS polymorphisms on 5-fluorouracil (5-FU) related toxicities and patient survival. Materials & methods: A total of 103 colorectal cancer patients prescribed 5-FU ... -
Oral Antidiyabetik Kullanımının, Farklılaşmış 3T3-L1 Hücrelerinde Adipogenez Metabolizmasında Görev Alan VDR, SIRT1, Apelin ve FOXO1 Gen Anlatım Seviyelerine Etkileri
Giriş: Yağ doku, obezite ve insülin direnci üzerindeki sistemik etkilere aracılık eden sitokinleri salgılamaktadır. Kullanılan antidiyabetik ilaçlar, 3T3-L1 adiposit hücrelerinde metabolik farklılıklar ve gen anlatım ... -
Warfarin pharmacogenetics in patients with heart valve replacement
Bezci, Kivanc; Cevik, Mehtap; Akdeniz, Cansu Selcan; Canbolat, Ismail Polat; Yurdakul, Selen; Sunbul, Murat; Susleyici, Belgin (Elsevier, 2020)Background: Warfarin treatment is crucial to prevent thrombolytic complications after the heart valve replacement (HVR) operation. Our purpose was to investigate the prevalence of CYP2C9 *2 and *3 gene polymorphisms, which ...
