Yazar "Degirmencioglu, Sevgin" için listeleme
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Anti-Inflammatory Effects of Melatonin in Rats with Induced Type 2 Diabetes Mellitus
Yapislar, Hande; Haciosmanoglu, Ebru; Sarioglu, Turkan; Degirmencioglu, Sevgin; Sogut, Ibrahim; Poteser, Michael; Ekmekcioglu, Cem (Mdpi, 2022)Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk for complications in patients with type 2 diabetes mellitus (T2DM). In addition to its chronobiotic effects, the pineal hormone ... -
Capsaicin Modulates Adipocyte Cell Differentiation and Inflammatory Gene Expression
Degirmencioglu, Sevgin; Cetinalp, Pinar; Seyithanoglu, Muhammed; Tanrikulu-Kucuk, Sevda; Kocak, Hikmet; Oner-Iyidogan, Yildiz (Istanbul Univ, 2024)Objective: Adipose tissue stores lipids necessary for the maintenance of nutritional homeostasis. It is also an endocrine organ that reacts to changes in inflammation and energy status. Capsaicin, the principal bioactive ... -
Ellagic Acid Enhances the Antitumor Efficacy of Bevacizumab in an in Vitro Glioblastoma Model
Cetin, Abdurrahman; Biltekin, Burcu; Degirmencioglu, Sevgin (Elsevier Science Inc, 2019)BACKGROUND: the anticarcinogenic effect of ellagic acid (EA), a natural phenol of fruits and vegetables, has been investigated in several types of tumors. the combined effect of EA with bevacizumab (BEV), a common drug ... -
IL-10, IL-13, IL-17 and CXCL8, CXCL10: Their relationship with the development and prognosis of type 1 and type 2 diabetes
Ebrahimzadeh, Mina; Pehlivanoglu, Cemil; Ozgur, Burcin Aydin; Kucuksezer, Umut Can; Degirmencioglu, Sevgin; Tekin, Sakin; Cakmak, Ramazan (Bayrakol Medical Publisher, 2023)Aim: Diabetes mellitus (DM) is a chronic high blood sugar disorder that can be classified into two groups: type 1 diabetes (T1D) and type 2 diabetes (T2D). The equilibrium between cytokines and chemokines is important for ... -
Investigatıon of Apoptotic Effects of Thymoquinone on Glioblastoma Cells
Cetinalp, Pinar; Geyik, Oyku Gonul; Malcanli, Senanur; Degirmencioglu, Sevgin; Kucuk, Sevda Tanrikulu; Kocak, Hikmet; Ulukaya, Engin (Springernature, 2025)BackgroundGlioblastoma multiforme (GBM) is the most aggressive and fatal primary brain tumor, characterized by rapid proliferation, resistance to therapy, and poor prognosis. Current treatment strategies, including surgery, ... -
Protective effects of boric acid on HBV-transgenic mice with chronic alcohol consumption: An experimental study
Erguven, Pelin; Tanrikulu-Kucuk, Sevda; Sevgin, Kubra; Degirmencioglu, Sevgin; Cetinalp, Pinar; Aksu, Soner; Gun-Atak, Palmet (Academic Press Inc Elsevier Science, 2025)This study aimed to investigate the protective effect of boric acid supplementation against liver damage in chronic alcohol-dependent HBV transgenic mice. The HBV transgenic mice were divided into four groups: control (C), ... -
The role of selenoprotein P and selenium in the etiopathogenesis of gestational diabetes mellitus: Association with selenoprotein P1 gene (rs3877899) polymorphism
Cinemre, F. Behice Serinkan; Cinemre, Hakan; Yucel, Ayse; Degirmencioglu, Sevgin; Tuten, Abdullah; Yuksel, M. Aytac; Aydemir, Birsen (DUSTRI-VERLAG DR KARL FEISTLE, 2018)Objective: The aim of this study was to investigate the role of selenoprotein P (SeP) and selenium in the etiopathogenesis of gestational diabetes mellitus (GDM) and their association with a common selenoprotein P1 (rs3877899) ...
