Yazar "Haciosmanoglu, Ebru" için listeleme
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Anti-Inflammatory Effects of Melatonin in Rats with Induced Type 2 Diabetes Mellitus
Yapislar, Hande; Haciosmanoglu, Ebru; Sarioglu, Turkan; Degirmencioglu, Sevgin; Sogut, Ibrahim; Poteser, Michael; Ekmekcioglu, Cem (Mdpi, 2022)Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk for complications in patients with type 2 diabetes mellitus (T2DM). In addition to its chronobiotic effects, the pineal hormone ... -
Cross-reacting material 197 (CRM197) affects actin cytoskeleton of endothelial cells
Edis, Bilge Ozerman; Varol, Basak; Haciosmanoglu, Ebru; Unlu, Ayhan; Bektas, Muhammet (GENERAL PHYSIOL AND BIOPHYSICS, 2017)CRM197, cross-reacting material 197, is a mutant of diphtheria toxin (DTx). CRM197 is used in pharmacology as a carrier protein. It has been recently shown that CRM197 causes breakdown in actin filaments. In order to show ... -
Interleukin-1 beta effect on the endogenous ADP-ribosylation and phosphorylation of eukaryotic elongation factor 2
Haciosmanoglu, Ebru; Varol, Basak; Edis, Bilge Ozerman; Bektas, Muhammet (SPRINGER, 2016)Eukaryotic elongation factor 2 (eEF2) plays an important role in eukaryotic polypeptide chain elongation. Adenosine diphosphate (ADP)-ribosylation is a post-translational modification reaction that catalyzes the transfer ... -
Intracellular trafficking of diphtheria toxin and its mutated form, CRM197, in the endocytic pathway
Edis, Bilge Ozerman; Haciosmanoglu, Ebru; Varol, Basak; Bektas, Muhammet (KARE PUBL, 2018)OBJECTIVE: Diphtheria toxin (DTx) is a well-characterized bacterial toxin. However, the endocytic pathway of the mutant of DTx, CRM197, which is used as an immunological adjuvant, has not yet been fully explained. The aim ... -
Noncovalent Pyrene-Polyethylene Glycol Coatings of Carbon Nanotubes Achieve in Vitro Biocompatibility
Meran, Mehdi; Akkus, Pelin Deniz; Kurkcuoglu, Ozge; Baysak, Elif; Hizal, Gurkan; Haciosmanoglu, Ebru; Guner, F. Seniha (AMER CHEMICAL SOC, 2018)Single-walled carbon nanotubes (SWNTs) have become increasingly exploited in biological applications, such as imaging and drug delivery. The application of SWNTs in biological settings requires the surface chemistry to ...
