Yazar "Taskiran, Dilek" için listeleme
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Accumulation of alpha-Synuclein in Cerebellar Purkinje Cells of Diabetic Rats and Its Potential Relationship with Inflammation and Oxidative Stress Markers
Solmaz, Volkan; Ozlece, Hatice Kose; Eroglu, Huseyin Avni; Aktug, Huseyin; Erbas, Oytun; Taskiran, Dilek (HINDAWI PUBLISHING CORP, 2017)Objective. The present study was conducted to evaluate the relationship between plasma oxidative stress markers such as malondialdehyde (MDA) and glutathione (GSH), inflammatory marker pentraxin-3 (PTX3), and cerebellar ... -
Comparison of the Effects of Extracorporeal Irradiation and Liquid Nitrogen on Nerve Recovery in a Rat Model
Kaya, Huseyin; Sabah, Dundar; Kececi, Burcin; Kucuk, Levent; Erbas, Oytun; Oltulu, Fatih; Taskiran, DilekAim of the study: Biologic reconstruction using tumor-bearing bone autografts devitalized by liquid nitrogen or extracorporeal irradiation (oncological sterilization) is a safe and effective method in musculoskeletal ... -
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study
Erbas, Oytun; Erdogan, Mumin Alper; Khalilnezhad, Asghar; Solmaz, Volkan; Gurkan, Fulya Tuzcu; Yigitturk, Gurkan; Taskiran, Dilek (WILEY, 2018)The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group ... -
Exenatide reduces TNF-alpha expression and improves hippocampal neuron numbers and memory in streptozotocin treated rats
Solmaz, Volkan; Cinar, Bilge Piri; Yigitturk, Gurkan; Cavusoglu, Turker; Taskiran, Dilek; Erbas, Oytun (ELSEVIER SCIENCE BV, 2015)Recent studies suggest a possible link between type 2 diabetes and Alzheimer's disease (AD). Glucoganlike peptide 1 (GLP-1) facilitates insulin release from pancreas under hyperglycemic conditions. In addition to its ... -
Exogenously administered adenosine attenuates renal damage in streptozotocin-induced diabetic rats
Taskiran, Emin; Erbas, Oytun; Yigitturk, Gurkan; Meral, Ayfer; Akar, Harun; Taskiran, Dilek (TAYLOR & FRANCIS LTD, 2016)Background: Diabetic nephropathy (DNP) is one of the most serious complications of diabetes mellitus (DM). In the present study, we investigated the potential of adenosine as a therapeutic candidate for preventing DNP.Methods: ... -
Granulocyte colony-stimulating factor provides protection against cardiovascular autonomic neuropathy in streptozotocin-induced diabetes in rats
Erbas, Oytun; Solmaz, Volkan; Taskiran, Dilek (ELSEVIER IRELAND LTD, 2015)Aims: Cardiovascular autonomic neuropathy (CAN) is a relatively common and detrimental complication of diabetes mellitus (DM). Dysregulation of neuropeptides, such as calcitonin gene-related peptide (CGRP) and vasoactive ... -
The investigation of therapeutic potential of oxytocin and liraglutide on vincristine-induced neuropathy in rats
Erdogan, Mumin A.; Taskiran, Emin; Yigitturk, Gurkan; Erbas, Oytun; Taskiran, Dilek (Wiley, 2020)The aim of this study was to assess the therapeutic potential of oxytocin and liraglutide (LIR), a GLP-1 analogue, in a rat model of vincristine-induced neuropathy. Rats were injected with vincristine (VCR) at a dose of 4 ... -
NEPHROPROTECTIVE EFFECT OF ADENOSINE IN STREPTOZOTOCIN INDUCED DIABETIC RATS
Taskiran, Emin; Erbas, Oytun; Yigitturk, Gurkan; Taskiran, Dilek; Akar, Harun (OXFORD UNIV PRESS, 2016)… -
Neurobehavioral effects of long-term maternal fructose intake in rat offspring
Erbas, Oytun; Erdogan, Mumin Alper; Khalilnezhad, Asghar; Gurkan, Fulya Tuzcu; Yigitturk, Gurkan; Meral, Ayfer; Taskiran, Dilek (PERGAMON-ELSEVIER SCIENCE LTD, 2018)Background: Previous studies have indicated an association between maternal metabolic conditions and general developmental disturbances of the offspring. Objective: We aimed to investigate the influence of long-term maternal ... -
Neuroprotective effects of chronic administration of levetiracetam in a rat model of diabetic neuropathy
Erbas, Oytun; Oltulu, Fatih; Yilmaz, Mustafa; Yavasoglu, Altug; Taskiran, Dilek (ELSEVIER IRELAND LTD, 2016)Objective: Diabetic neuropathy (DNP) is a frequent and serious complication of diabetes mellitus (DM) that leads to progressive and length-dependent loss of peripheral nerve axons. The purpose of the present study is to ... -
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats
Erdogan, Mumin Alper; Yigitturk, Gurkan; Erbas, Oytun; Taskiran, Dilek (Taylor & Francis Ltd, 2021)Aim Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ... -
Neuroprotective effects of octreotide on diabetic neuropathy in rats
Solmaz, Volkan; Cinar, Bilge Piri; Yigitturk, Gurkan; Ozlece, Hatice Kose; Eroglu, Huseyin Avni; Tekatas, Aslan; Taskiran, Dilek (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017)The purpose of the present study is to investigate the possible healing effects of octreotide (OCT) on motor performance, electrophysiological and histopathological findings of diabetic neuropathy in a rat model of diabetes ... -
Oxytocin provides protection against diabetic polyneuropathy in rats
Erbas, Oytun; Taskiran, Dilek; Oltulu, Fatih; Yavasoglu, Altug; Bora, Saylav; Bilge, Okan; Peker, Gonul (TAYLOR & FRANCIS LTD, 2017)Purpose: The aim of the present study is to investigate the protective effects of oxytocin (OT) on diabetic neuropathy (DNP) in rats. Materials and methods: Eighteen rats were used to induce diabetes using single dose ... -
The potential effects of anticonvulsant drugs on neuropeptides and neurotrophins in pentylenetetrazol kindled seizures in the rat
Tekgul, Hasan; Simsek, Erdem; Erdogan, Mumin Alper; Yigitturk, Gurkan; Erbas, Oytun; Taskiran, Dilek (Taylor & Francis Ltd, 2020)Purpose: Neuropeptides and neurotrophic factors are thought to be involved in epileptogenesis. This study aims to investigate the potential effects of anticonvulsant drugs on neuropeptides (galanin and neuropeptide Y) and ... -
The Preventive Effect of Oxytocin on Retinopathy in Streptozotocin-Induced Diabetic Rats
Degirmenci, Cumali; Afrashi, Filiz; Erbas, Oytun; Aktug, Huseyin; Taskiran, Dilek (TURKISH OPHTHALMOLOGICAL SOC, 2019)Objectives: The aim of this study was to investigate the impact of intravitreal and intraperitoneal use of oxytocin (OT) on retinopathy in streptozotocin-induced diabetic rats. Materials and Methods: Twenty-four 6-8-week-old ... -
The Prophylactic Effects of Metoprolol, Diltiazem, and Pilocarpine on Hypoglycemia-Induced Prolongation of QT Interval
Cagiltay, Eylem; Pouwels, Sjaak; Erbas, Oytun; Taskiran, Dilek; Tas, Sevgi Kalkanli; Aslan, Ismael (Cureus Inc, 2021)Background Insulin-induced hypoglycemia has been demonstrated to prolong the corrected QT (QTc) interval. Prolongation of the QTc interval, especially in diabetic patients using insulin, can cause fatal ventricular ... -
Protection by Edaravone, a Radical Scavenger, against Manganese-Induced Neurotoxicity in Rats
Apaydin, Melda; Erbas, Oytun; Taskiran, Dilek (WILEY-BLACKWELL, 2016)Manganese (Mn) is a required element for biological systems; however, its excessive exposure may lead to a neurological syndrome known as manganism. The aim of the present study was to assess the toxic effects of subacute ...
