Yazar "Yavasoglu, Altug" için listeleme
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The antioxidant role of agomelatine and gallic acid on oxidative stress in STZ induced type I diabetic rat testes
Yigitturk, Gurkan; Acara, Ahmet Cagdas; Erbas, Oytun; Oltulu, Fatih; Yavasoglu, Nefise Ulku Karabay; Uysal, Aysegul; Yavasoglu, Altug (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017)Diabetes is a multisystem disorder and its effects are observed on the reproductive system. One of the main causes of testicular tissue damage is diabetes-induced overproduction of reactive oxygen species and glycated end ... -
Exenatide preserves trabecular bone microarchitecture in experimental ovariectomized rat model
Eminov, Elmin; Hortu, Ismet; Akman, Levent; Erbas, Oytun; Yavasoglu, Altug; Cirpan, Teksin (SPRINGER HEIDELBERG, 2018)Purpose The aim of this study is to investigate effects of exenatide (Glucagon-Like Peptide Agonist) replacement on bone mineral density (BMD) and microarchitecture in a surgical menopause-induced osteoporosis model in ... -
Neuroprotective effects of chronic administration of levetiracetam in a rat model of diabetic neuropathy
Erbas, Oytun; Oltulu, Fatih; Yilmaz, Mustafa; Yavasoglu, Altug; Taskiran, Dilek (ELSEVIER IRELAND LTD, 2016)Objective: Diabetic neuropathy (DNP) is a frequent and serious complication of diabetes mellitus (DM) that leads to progressive and length-dependent loss of peripheral nerve axons. The purpose of the present study is to ... -
Oxidative stress and inflammatory markers in streptozotocin-induced acute and subacute toxicity response
Sanci, Ebru; Koksal Karayildirim, Cinel; Dagdeviren, Melih; Yigitturk, Gurkan; Buhur, Aylin; Erbas, Oytun; Yavasoglu, Altug (Taylor & Francis Ltd, 2024)Streptozotocin (STZ) is used as a diabetes-inducing agent in experimental animal studies. However, it is known that STZ-induced diabetic animals show significant increases in oxidative stress parameters and neurodegeneration ... -
Oxytocin provides protection against diabetic polyneuropathy in rats
Erbas, Oytun; Taskiran, Dilek; Oltulu, Fatih; Yavasoglu, Altug; Bora, Saylav; Bilge, Okan; Peker, Gonul (TAYLOR & FRANCIS LTD, 2017)Purpose: The aim of the present study is to investigate the protective effects of oxytocin (OT) on diabetic neuropathy (DNP) in rats. Materials and methods: Eighteen rats were used to induce diabetes using single dose ... -
Silymarin ameliorates uterine and ovarian damage in streptozotocin induced diabetic rat model
Yildirim, Nuri; Kose, Semir; Yildirim, AlkimGulsahSahingoz; Sahin, Cagdas; Yigitturk, Gurkan; Yavasoglu, Altug; Erbas, Oytun (NATL INST SCIENCE COMMUNICATION-NISCAIR, 2018)Diabetes is a systemic disease that affects microvasculature in almost all organs. Uterus and the ovaries may also be a target for diabetes. We investigated effects of diabetes on the uterus and the ovaries and the role ... -
Therapeutic effect of sunitinib on diabetes mellitus related ovarian injury: an experimental rat model study
Erbas, Oytun; Pala, Halil Gursoy; Pala, Emel Ebru; Ulkumen, Burcu Artunc; Akman, Levent; Akman, Tulay; Yavasoglu, Altug (INFORMA HEALTHCARE, 2015)The aim of our study is to investigate the effect of sunitinib on diabetes mellitus related-ovarian injury and fibrosis in rat models. An experimental diabetes mellitus model was created in 16 rats, and eight rats with ...