Yayıncı "Acta Cirurgica Brasileira" için listeleme
Toplam kayıt 6, listelenen: 1-6
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Antifibrotic preventive effect of polyethylene glycol (PEG) 3350 in methotrexate-induced hepatoxicity model
(Acta Cirurgica Brasileira, 2022)Purpose: Liver damage caused by drugs and other chemicals accounts for about 5% of all cases. Methotrexate (MTX), a folic acid analogue, is a first-line synthetic antimetabolite agent routinely used in the treatment of ... -
Autophagy and anti-inflammation ameliorate diabetic neuropathy with Rilmenidine
(Acta Cirurgica Brasileira, 2023)Purpose: To evaluate the neuroprotective effects of Rilmenidine on diabetic peripheral neuropathy (DPN) in a rat model of diabetes induced by streptozotocin (STZ). Methods: STZ (60 mg/kg) was administered to adult ... -
Caffeine mitigates tamoxifen-induced fatty liver in Wistar rats
(Acta Cirurgica Brasileira, 2024)Purpose: Tamoxifen, a widely used drug for breast cancer treatment, is associated with adverse effects on the liver, including the development of fatty liver. This study aimed to investigate the potential protective effect ... -
Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model
(Acta Cirurgica Brasileira, 2022)Purpose: To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats. Methods: Thirty male Wistar albino rats were used. Rats were randomly divided into three equal groups, and ... -
Therapeutic effect of adenosine on experimentally induced acute ulcerative colitis model in rats
(Acta Cirurgica Brasileira, 2019)Purpose: To examine the therapeutic effect of external adenosine on an acetic acid-induced acute ulcerative colitis model in rats. Methods: Thirty male mature rats were divided into three groups as control, acute colitis ... -
Therapeutic effects of vitamin D on acetic acid-induced colitis in rats
(Acta Cirurgica Brasileira, 2020)Purpose: To analyze the effect of calcitriol treatment on acute colitis in an experimental rat model. Methods: A total of 24 adult Sprague Dawley albino rats were randomly separated into 3 equal groups: control group (n:8), ...