Browsing by Author "Akdeniz, Cansu Selcan"
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The effects of CYP2C9 and VKORC1 gene polymorphisms on warfarin maintenance dose in Turkish cardiac patients
Akdeniz, Cansu Selcan; Cevik, Mehtap; Canbolat, Ismail Polat; Yurdakul, Selen; Cagatay, Penbe; Ciftci, Cavlan; Karaalp, Atila (Future Medicine Ltd, 2020)Aim: Our aim was to examine the effect of CYP2C9 and VKORC1 polymorphisms on warfarin dose requirements in Turkish patients. Materials & methods: 24 warfarin prescribed patients were included and analyzed for eight VKORC1 ... -
Glycoprotein Ib alpha Kozak polymorphism in patients presenting with early-onset acute coronary syndrome
Golcuk, Ebru; Yalin, Kivanc; Akdeniz, Cansu Selcan; Teker, Erhan; Teker, Basak; Hancer, Veysel Sabri; Oncul, Aytac (TERMEDIA PUBLISHING HOUSE LTD, 2018)Introduction: Glycoprotein Ib alpha (GPIb alpha) receptor is the chief molecule responsible for initial platelet adhesion to the subendothelium. A thymidine to cytosine single nucleotide substitution at position -5 from ... -
Postoperative Myocardial Injury Does Not Predict Early and 1-Year Mortality After Living Donor Liver Transplantation
Canbolat, Ismail Polat; Adali, Gupse; Akdeniz, Cansu Selcan; Bozkurt, Birkan; Feran, Oya; Bulutcu, Fisun; Tokat, Yaman (Elsevier Science Inc, 2019)Background. Preoperative cardiac troponin-I (cTnI) elevation has been shown to be a predictor of mortality after liver transplantation. Myocardial injury after non-cardiac surgery (MINS) has been defined as elevation of ... -
Warfarin pharmacogenetics in patients with heart valve replacement
Bezci, Kivanc; Cevik, Mehtap; Akdeniz, Cansu Selcan; Canbolat, Ismail Polat; Yurdakul, Selen; Sunbul, Murat; Susleyici, Belgin (Elsevier, 2020)Background: Warfarin treatment is crucial to prevent thrombolytic complications after the heart valve replacement (HVR) operation. Our purpose was to investigate the prevalence of CYP2C9 *2 and *3 gene polymorphisms, which ...