Browsing by Author "Altıok, Nedret"

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Estradiol induces JNK-dependent apoptosis in glioblastoma cells

Altıok, Nedret; Ersöz, Melike; Koyutürk, Meral (Spandidos Publications, 2011)

Estrogens exert multiple regulatory actions on cellular events in a variety of tissues including the brain. In the present study, the signaling mechanisms of the concentration-dependent effects of 17-β-estradiol (estradiol) ...
İnsan endometriyal kanser hücrelerinde östrojenin konsantrasyona bağlı etkilerinin incelenmesi

Atvar, Özhan (İstanbul Bilim Üniversitesi, Sağlık Bilimleri Enstitüsü., 2006)

Östrojenin insan uterusunda endometriyal hücrelerin büyüme ve gelişmesini uyardığı bilinmektedir. Östrojenin endometriyal hücreler üzerindeki etkilerini karakterize etmek için iyi diferansiye insan endometriyal kanserinden ...
Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK

Koyutürk, Meral; Ersöz, Melike; Altıok, Nedret (Elsevier, 2007)

The effect of simvastatin, a widely used statin for the treatment of hypercholesterolemia, was investigated in the estrogen receptor (ER)-positive MCF-7, and the ER-negative MDA-MB 231 human breast cancer cell lines. ...