Browsing by Author "Cagatay, Penbe"

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The effects of CYP2C9 and VKORC1 gene polymorphisms on warfarin maintenance dose in Turkish cardiac patients

Akdeniz, Cansu Selcan; Cevik, Mehtap; Canbolat, Ismail Polat; Yurdakul, Selen; Cagatay, Penbe; Ciftci, Cavlan; Karaalp, Atila (Future Medicine Ltd, 2020)

Aim: Our aim was to examine the effect of CYP2C9 and VKORC1 polymorphisms on warfarin dose requirements in Turkish patients. Materials & methods: 24 warfarin prescribed patients were included and analyzed for eight VKORC1 ...
Firmicutes/Bacteroidetes Ratio in the Gut Microbiota and IL-10, IL-6, IL-8, TLR2, TLR4, TLR5 Gene Expressions in Type 2 Diabetes

Bahar-Tokman, Hrisi; Demirci, Mehmet; Keskin, Fatma E.; Cagatay, Penbe; Taner, Zeynep; Ozturk-Bakar, Yesim; Ozyazar, Mucahit (Clin Lab Publ, 2022)

Background: The aim of this study was to determine the Firmicutes/Bacteroidetes ratio in the gut microbiota and IL-1 beta, IL-6, IL-8, TLR2, TLR4 and TLR5 gene expression levels in the blood of adult type 2 diabetes (T2D) ...
Investigation of DPYD, MTHFR and TYMS polymorphisms on 5-fluorouracil related toxicities in colorectal cancer

Cevik, Mehtap; Namal, Esat; Sener, Nur Dinc; Koksal, Ulkuhan Iner; Cagatay, Penbe; Deliorman, Gokce; Susleyici, Belgin (Future Medicine Ltd, 2022)

Aim: To investigate the association of DPYD, MTHFR and TYMS polymorphisms on 5-fluorouracil (5-FU) related toxicities and patient survival. Materials & methods: A total of 103 colorectal cancer patients prescribed 5-FU ...