Browsing by Author "Madhusudhan, Thati"

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Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function

Madhusudhan, Thati; Wang, Hongjie; Ghosh, Sanchita; Dong, Wei; Kumar, Varun; Al-Dabet, Moh'd Mohanad; Isermann, Berend (AMER SOC HEMATOLOGY, 2017)

Coagulation proteases have increasingly recognized functions beyond hemostasis and thrombosis. Disruption of activated protein C (aPC) or insulin signaling impair function of podocytes and ultimately cause dysfunction of ...