Browsing by Author "Saglam, Sezer"

Can Megestrol Acetate Induce Thrombosis in Advanced Oncology Patients Receiving Chemotherapy?

Ordu, Cetin; Pilanci, Kezban Nur; Koksal, Ulkuhan Iner; Okutur, Kerem; Saglam, Sezer; Tecimer, Coskun; Demir, Gokhan (ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2014)

Background: Megestrol acetate (MA) is a steroid origin medicine often used for control of cachexia in oncologic palliative care. Thrombosis is a common problem in oncology patients. One question is whether MA can cause ...

Chronomodulated Administration of Oxaliplatin plus Capecitabine (XELOX) as First Line Chemotherapy in Metastatic Colorectal Cancer Patients: Phase II Brunch Regimen Study.

Pilanci, Kezban Nur; Saglam, Sezer; Okyar, Alper; Yucel, Serap; Kara, Zeliha Pala; Ordu, Cetin; Saglam, Esra Kaytan (AMER SOC CLINICAL ONCOLOGY, 2015)

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Chronomodulated oxaliplatin plus Capecitabine (XELOX) as a first line chemotherapy in metastatic colorectal cancer: A Phase II Brunch regimen study

Pilanci, Kezban Nur; Saglam, Sezer; Okyar, Alper; Yucel, Serap; Pala-Kara, Zeliha; Ordu, Cetin; Kaytan-Saglam, Esra (SPRINGER, 2016)

The aim of this study was to evaluate safety and toxicity of chronomodulated capecitabine administered in the morning and at noon according to a specific time schedule (Brunch Regimen: Breakfast and Lunch) as a part of ...

Delayed versus immediate surgery following short-course neoadjuvant radiotherapy in resectable (T3N0/N+) rectal cancer

Kaytan-Saglam, Esra; Balik, Emre; Saglam, Sezer; Akgun, Zuleyha; Ibis, Kamuran; Keskin, Metin; Gulluoglu, Mine (SPRINGER, 2017)

Purpose Preoperative short-course radiotherapy (SCRT) followed by surgery has shown advantage over surgery alone in patients with resectable rectal carcinoma (RC); however, the importance of the timing of surgery after ...

Gallbladder Uptake Mimicking Liver Metastasis on Lu-177-DOTATATE Posttherapy Scan Gallbladder Uptake on Lu-177-DOTATATE Scan

Araz, Mine; Baltacioglu, Muhammet Halil; Saglam, Sezer; Ozguven, Mehmet Ali; Kucuk, Nuriye Ozlem (Lippincott Williams & Wilkins, 2021)

We represent the case of a 61-year-old man with atypical carcinoid tumor of the lung. On posttherapy Lu-177-DOTATATE whole-body scan, focal intense uptake in the inferomedial side of the liver was detected. Pretherapy ...

IS CHROMOSOMAL RADIOSENSITIVITY A PREDICTIVE TOOL FOR CANCER RISKS?

Ozar, Melek Ozlem Kolusayin; Orta, Tuncay; Dizdar, Yavuz; Saglam, Esra Kaytan; Saglam, Sezer; Turna, Akif; Okutan, Murat (Parlar Scientific Publications (P S P), 2021)

There is an extensive landscape of genomic disruptions caused by environmental carcinogens. A major environmental mutagen that can trigger direct changes in the DNA is radiation. In certain places, ionizing radiation such ...

Neoadjuvant chronomodulated capecitabine with radiotherapy in rectal cancer: a phase II brunch regimen study

Akgun, Zuleyha; Saglam, Sezer; Yucel, Serap; Gural, Zeynep; Balik, Emre; Cipe, Gokhan; Kaytan-Saglam, Esra (SPRINGER, 2014)

The aim of this study was to evaluate efficacy and safety of chronomodulated capecitabine administered according to a specific time schedule (Brunch Regimen: Breakfast and Lunch) as a part of neoadjuvant chemoradiation ...

Neoadjuvant hyperfractionated accelerated radiotherapy plus concomitant 5-fluorouracil infusion in locally advanced rectal cancer: A phase. study

Gural, Zeynep; Saglam, Sezer; Yucel, Serap; Kaytan-Saglam, Esra; Asoglu, Oktar; Ordu, Cetin; Oral, Ethem N. (BAISHIDENG PUBLISHING GROUP INC, 2018)

AIM To evaluate the efficacy and tolerability of neoadjuvant hyperfractionated accelerated radiotherapy (HART) and concurrent chemotherapy in patients with locally advanced infraperitoneal rectal cancer. METHODS A total ...

Neoadjuvant intermediate-course versus long-course chemoradiotherapy in T3-4/N0+rectal cancer: Istanbul R-02 phase II randomized study

Senyurek, Sukran; Saglam, Sezer; Saglam, Esra Kaytan; Yanar, Hakan; Gok, Kaan; Tastekin, Didem; Akbas, Canan Koksal (Tech Science Press, 2023)

Radiation therapy (RT) is typically applied using one of two standard approaches for preoperative treatment of resectable locally advanced rectal cancer (LARC): short-course RT (SC-RT) alone or long-course RT (LC-RT) with ...

A new approach for leptomeningeal metastases: chemotherapy administered through lumbar intrathecal port

Comlek, Savas; Saglam, Sezer (Assoc Arquivos Neuro- Psiquiatria, 2021)

Background: Intrathecal chemotherapy is a local therapeutic modality used for treatment of leptomeningeal metastases. However, the techniques currently used, i.e. repeated lumbar puncture and Ommaya reservoir, have certain ...

Primary large cell prostate neuroendocrine carcinoma with central and nephrogenic diabetes insipidus

Basatac, Cem; Saglam, Sezer; Aktepe, Fatma; Akpinar, Haluk (Brazilian Soc Urol, 2020)

[No abstract available]

Primary renal angiosarcoma with progressive clinical course despite surgical and adjuvant treatment: A case report

Celebi, Filiz; Pilanci, Kezban Nur; Saglam, Sezer; Balci, Numan Cem (SPANDIDOS PUBL LTD, 2015)

Angiosarcoma is an extremely rare, high-grade malignancy, which accounts for <2% of all soft-tissue sarcomas. Cases of primary renal angiosarcoma represent 1% of these. Angiosarcomas involving the kidney usually originate ...

Prognostic Significance of CA IX Overexpression in Stage III NSCLC Patients Received Neoadjuvant Treatment

Saglam, Sezer; Ibis, Kamuran; Saglam, Esra Kaytan; Firat, Pinar; Yilmazbayhan, Dilek; Toker, Alper; Disci, Rian (ELSEVIER SCIENCE INC, 2017)

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Prognostic significance of carbonic anhydrase IX overexpression in stage III non-small cell lung cancer patients after neoadjuvant treatment

Ibis, Kamuran; Saglam, Sezer; Saglam, Esra Kaytan; Firat, Pinar; Yilmazbayhan, Dilek; Toker, Alper; Pilanci, Kezban Nur (ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2018)

Background: To assess the prognostic importance of carbonic anhydrase IX (CA IX), a hypoxic biomarker, after neoadjuvant treatment in Stage III non-small cell lung cancer (NSCLC) patients. Methods: Tissue CA IX expression ...

Robotic vs. laparoscopic intersphincteric resection for low rectal cancer: a case matched study reporting a median of 7-year long-term oncological and functional outcomes

Aliyev, Vusal; Piozzi, Guglielmo Niccolo; Bulut, Alisina; Guven, Koray; Bakir, Baris; Saglam, Sezer; Asoglu, Oktar (Springer-Verlag Italia Srl, 2022)

Aim of this study was to compare operative, long-term oncological and functional outcomes of laparoscopic (LISR) and robotic (RISR) intersphincteric resection in low-lying rectal cancer. Retrospective analysis of prospectively ...