Browsing by Author "Sakalli, Eren"
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Anticonvulsant activity of 3,5-dimethylpyrazole derivatives in animal models
Kocyigit-Kaymakcioglu, Bedia; Aker, Rezzan Gulhan; Tezcan, Kutluhan; Sakalli, Eren; Ketenci, Sema; Oruc-Emre, Emine Elcin; Rollas, Sevim (BIRKHAUSER BOSTON INC, 2011)A series of 3,5-dimethylpyrazole derivatives, structurally related to the previously described potent ameltolide analogues, were synthesized and evaluated for their anticonvulsant activity. Ten compounds were prepared by ... -
Localized cortical injections of ethosuximide suppress spike-and-wave activity and reduce the resistance to kindling in genetic absence epilepsy rats (GAERS)
Aker, Rezzan Guelhan; Tezcan, Kutluhan; Carcak, Nihan; Sakalli, Eren; Akin, Demet; Onat, Filiz Yilmaz (ELSEVIER SCIENCE BV, 2010)Models of genetic absence epilepsy are resistant to secondary generalization of focal limbic seizures. This correlates with the postnatal development of spike-and-wave discharges (SWDs), a hallmark of absence seizures ...