Browsing by Author "Yapışlar, Hande"
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Altered erythrocyte deformability and antioxidant status in patients with schizophrenia
Yapışlar, Hande (Marmara Üniversitesi Tıp Fakültesi, 2012)Objective: Schizophrenia is a major mental disorder whose etiology still remains unkown. There is evidence that free radicals are involved in membrane pathology in the central nervous system and may play a role in the ... -
Antioxidant effect of carnosine treatment on renal oxidative stress in streptozotocin-induced diabetic rats.
Yay, Arzu; Akkuş, Didem; Yapışlar, Hande; Balcıoğlu, Esra; Sönmez, Mehmet F; Özdamar, Saim (Taylor and Francis Online, 2014)Nitric oxide (NO) plays a significant role in the development of diabetic nephropathy. We investigated the effects of an antioxidant, carnosine, on streptozotocin (STZ)-induced renal injury in diabetic rats. We used four ... -
Diyabetin ve karnozinin kemik yapısı ve mineral yoğunluğu üzerine etkileri
Yay, Arzu; Balcıoğlu, Esra; Yapışlar, Hande; Özdamar, Saim (Erciyes Üniversitesi Sağlık Bilimleri Enstitüsü, 2013)Bu çalışmada streptozotosin (STZ) ile oluşturulan diyabetin sıçan femurundaki kemik yapısı ile mineral yoğunluğunda oluşturduğu değişiklikler ve bu değişiklikler üzerine karnozinin yararlı etkisinin olup olmadığını belirlemek ... -
Effect of coffee extracts on intracellular calcium level in levels in glial cells
Akın, Demet; Görmüş, Uzay; Yapışlar, Hande; Farah, Adriana (ASIC 2012 International Conference - Costa Rica, 2012)Widely used antidepressant drugs such as fluoxetine exert additional blocking effects on voltage gated Ca⁺² channels. Differences in intracellular calcium levels may be involved in the release of monoamines, which play ... -
Evaluation of carbapenem resistance using phenotypic and genotypic techniques in enterobacteriaceae isolates.
Şahin, Kazım; Tekin, Ayşe; Özdaş, Şule; Akın, Demet; Yapışlar, Hande; Dilek, Aziz Ramazan; Sönmez, Emine (BioMed Central, 2015)Background: Bacterial resistance to antibiotics is increasing worldwide. Antibiotic-resistant strains can lead to serious problems regarding treatment of infection. Carbapenem antibiotics are the final treatment option for ... -
How carnosine affects cardiovascular parameters in remnant kidney model
Yapışlar, Hande; Taşkın, Eylem (2013)Puropse. Chronic kidney disease (CKD) is a majör public health concern affecting millions of people. Oxidative stress is a mediator of sytemic complications of chronic renal failure (CRF) and involved in the pathogenesis ... -
L-carnosine alters some hemorheologic and lipid peroxidation parameters in nephrectomized rats
Yapışlar, Hande; Taşkın, Eylem (Int Scientific Literature, 2014)Background: Chronic kidney disease (CKD) is a major health problem worldwide. Oxidative stress is one of the mediators of this disease. Systemic complications of oxidative stress are involved in the pathogenesis of ... -
Melatonin's effect on inflammatory cytokines in oxidative stress induced PC12 cells
Yapışlar, Hande; Özdaş, Şule; Akın, Demet; Ersöz, Melike (Wiley Online Library, 2013)Introduction: Melatonin is primarily synthesized and secreted by the pineal gland. Melatonin participate in many physiological and biochemical functions. The etiology of neurodegenerative diseases has not been well understood. -
Nephro-protective effect of granulocyte colony-stimulating factor in streptozotocin induced diabetic rats
Erbaş, Oytun; Yapışlar, Hande; Oltulu, Fatih; Yavaşoğlu, Altuğ; Aktuğ, Hüseyin; Taşkıran, Dilek (Informahealthcare, 2014)Diabetic nephropathy is one of the most serious complications of diabetes and the major cause of end-stage renal failure. Consequences of diabetic nephropathy include increased kidney size and glomerular volume, thickening ...
