Ara
Toplam kayıt 18, listelenen: 11-18
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study
(WILEY, 2018)
The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group ...
Neurobehavioral effects of long-term maternal fructose intake in rat offspring
(PERGAMON-ELSEVIER SCIENCE LTD, 2018)
Background: Previous studies have indicated an association between maternal metabolic conditions and general developmental disturbances of the offspring. Objective: We aimed to investigate the influence of long-term maternal ...
Octreotide protects ovary against ischemia-reperfusion injury in rats: Evaluation of histological and biochemical parameters
(WILEY-BLACKWELL, 2015)
AimThis study investigated the efficacy of octreotide for prevention of ischemia-reperfusion injury in rat ovary. MethodsThirty-two adult female rats were included. Rats were divided into five groups: in the sham group, ...
The antioxidant role of agomelatine and gallic acid on oxidative stress in STZ induced type I diabetic rat testes
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017)
Diabetes is a multisystem disorder and its effects are observed on the reproductive system. One of the main causes of testicular tissue damage is diabetes-induced overproduction of reactive oxygen species and glycated end ...
Neuroprotective effects of erythropoietin on Alzheimer's dementia model in rats
(WROCLAW MEDICAL UNIV, 2017)
Background. Although Alzheimer's disease (AD) is the most common age-related neurodegenerative disease and characterized by memory impairment, only symptomatic treatments are available. Objectives. Because recombinant human ...
Exenatide reduces TNF-alpha expression and improves hippocampal neuron numbers and memory in streptozotocin treated rats
(ELSEVIER SCIENCE BV, 2015)
Recent studies suggest a possible link between type 2 diabetes and Alzheimer's disease (AD). Glucoganlike peptide 1 (GLP-1) facilitates insulin release from pancreas under hyperglycemic conditions. In addition to its ...
Exogenously administered adenosine attenuates renal damage in streptozotocin-induced diabetic rats
(TAYLOR & FRANCIS LTD, 2016)
Background: Diabetic nephropathy (DNP) is one of the most serious complications of diabetes mellitus (DM). In the present study, we investigated the potential of adenosine as a therapeutic candidate for preventing DNP.Methods: ...
Antifibrotic Effect of Lactulose on a Methotrexate-Induced Liver Injury Model
(HINDAWI LTD, 2017)
The most severe side effect of prolonged MTX treatment is hepatotoxicity. The aim of this study is to investigate the effect of lactulose treatment on MTX-induced hepatotoxicity in a rat model. Twenty-four male rats were ...