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Toplam kayıt 8, listelenen: 1-8
Research Article Nasal Oxytocin's Anticonvulsant Effects on Pentylenetetrazolinduced Convulsions in Rats
(Asian Network Scientific Information-Ansinet, 2023)
Background and Objective: Neurodegenerative proteins and pro-inflammatory mechanisms may cause epilepsy through excitatory-inhibitory imbalance. Drug resistance is common, therefore this disease requires affordable, ...
Effects of prenatal testosterone exposure on the development of autism-like behaviours in offspring of Wistar rats
(Wiley, 2023)
BackgroundA neurodevelopmental disease, autism spectrum disorder (ASD) occurs in males three times more commonly than girls. Higher prenatal testosterone exposure may result in autistic-like behaviour in boys, according ...
The Healing Effect of Digoxin on Peripheral Nerve Damage and Its Relation to IL-17/IL-10
(Turkish Neurosurgical Soc, 2023)
AIM: To demonstrate the curative effect of digoxin on peripheral nerve damage with its anti-inflammatory role on interleukin (IL)-17. MATERIAL and METHODS: The study was conducted with 30 male Sprague Dawley albino mature ...
Demonstration of the protective effect of propofol in rat model of cisplatin-induced neuropathy
(Aepress Sro, 2023)
Cisplatin is commonly used in the treatment of lung, genitourinary, and gastrointestinal cancers. Peripheral neuropathy is the most important side effect, leading to a decrease in the dose of cisplatin or its complete ...
N-acetyl cysteine: A new look at its effect on PTZ-induced convulsions
(Elsevier, 2023)
Introduction/Aim: Epilepsy is widely investigated as a common neurological disease requiring pharmacologically effective agents. N-acetyl cysteine (NAC), has become a remarkable molecule with its role in both antioxidant ...
Protective Effects of Ibudilast Against Cisplatin-Induced Hepatotoxicity and Nephrotoxicity Mediated by Prostacyclin Enhancement
(Asian Network Scientific Information-Ansinet, 2023)
Background and Objective: Cisplatin, a prevalent chemotherapy drug, presents hepatotoxic and nephrotoxic side effects, this study explores ibudilast's potential protective effects against such damage via prostacyclin ...
Immunosuppressant Tacrolimus Treatment Delays Acute Seizure Occurrence, Reduces Elevated Oxidative Stress, and Reverses PGF2? Burst in the Brain of PTZ-Treated Rats
(Springer/Plenum Publishers, 2023)
It is still an urgent need to find alternative and effective therapies to combat epileptic seizures. Tacrolimus as a potent immunosuppressant and calcineurin inhibitor is emerging as promising drug to suppress seizures. ...
Effects of Diclofenac Sodium on Seizure Activity in Rats with Pentylenetetrazole-Induced Convulsions
(Springer/Plenum Publishers, 2023)
Epilepsy is a disease which affects between 1 and 2% of the population, and a large proportion of these people do not react to currently available anticonvulsant medications, indicating the need for further research into ...