Ara
Toplam kayıt 11, listelenen: 1-10
Neuroprotective Effects of Eexenatide in a Rotenone-Induced Rat Model of Parkinson's Disease
(ELSEVIER SCIENCE INC, 2017)
Backround: Several studies suggest an association between Parkinson's disease (PD) and type 2 diabetes mellitus; these 2 diseases are both known to affect the common molecular pathways. As a synthetic agonist for the ...
Antipsychotic Like Effects of Atorvastatin and Melatonin in a Psychosis Model in Rats
(YERKURE TANITIM & YAYINCILIK HIZMETLERI A S, 2015)
Objective: In recent years besides dopaminergic imbalance exhibition of other possible mechanisms like inflammation and serotonergic abnormalities have pointed out the need for new antipsychotic drugs. In this study our ...
Pentilentetrazol ile oluşturulan konvülziyon modelinde metilen mavisi ve tadalafilin etkileri
(2016)
L-Arjinin (L-ARG) -nitrik oksid (NO) -cGMP (siklik guanozin monofosfat) döngüsünün epilepsideki rolünü gösteren bazı çalışmalar vardır. Tadalafil, fosfodiesteraz-5 (PDE5) 'in güçlü bir inhibitörüdür ve cGMP'nin etkisini ...
Highly selective SGLT2 inhibitor dapagliflozin reduces seizure activity in pentylenetetrazol-induced murine model of epilepsy
(BIOMED CENTRAL LTD, 2018)
Background: Worldwide, over 10 million individuals suffer from drug-resistant epilepsy. New therapeutic strategies are needed to address this debilitating disease. Inhibition of sodium-glucose linked transporters (SGLTs), ...
Rebaudioside A inhibits pentylenetetrazol-induced convulsions in rats
(ELSEVIER TAIWAN, 2016)
The safety of patients with epilepsy consuming sweetening agents, which is becoming increasingly prevalent for various reasons, is a topic that should be emphasized as sensitively as it is for other diseases. Patients with ...
Inhibitor effect of paricalcitol in rat model of pentylenetetrazol-induced seizures
(SPRINGER, 2016)
Vitamin D has various systemic effects on bone metabolism, modulation of the immune system, stabilization of the cell membrane, oxidative stress, inflammation, apoptosis, and various other hormones. Differing from active ...
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study
(WILEY, 2018)
The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group ...
Accumulation of alpha-Synuclein in Cerebellar Purkinje Cells of Diabetic Rats and Its Potential Relationship with Inflammation and Oxidative Stress Markers
(HINDAWI PUBLISHING CORP, 2017)
Objective. The present study was conducted to evaluate the relationship between plasma oxidative stress markers such as malondialdehyde (MDA) and glutathione (GSH), inflammatory marker pentraxin-3 (PTX3), and cerebellar ...
Granulocyte colony-stimulating factor provides protection against cardiovascular autonomic neuropathy in streptozotocin-induced diabetes in rats
(ELSEVIER IRELAND LTD, 2015)
Aims: Cardiovascular autonomic neuropathy (CAN) is a relatively common and detrimental complication of diabetes mellitus (DM). Dysregulation of neuropeptides, such as calcitonin gene-related peptide (CGRP) and vasoactive ...
Neuroprotective effects of erythropoietin on Alzheimer's dementia model in rats
(WROCLAW MEDICAL UNIV, 2017)
Background. Although Alzheimer's disease (AD) is the most common age-related neurodegenerative disease and characterized by memory impairment, only symptomatic treatments are available. Objectives. Because recombinant human ...