Giriş: Trombosit aktivasyonu ve agregasyonunun inhibe edilmesi akut koroner sendrom ve perkutan koroner girişim sonrasında kritik öneme sahiptir. Klopidogrel tienopiridin türevi bir ilaç olup, etkisini trombosit agregasyonunu ...

Objective: Clopidogrel inhibits platelet aggregation by blockade of platelet adenosine diphosphate (ADP) P2Y12 receptor. Leptin is the obesity gene product, and its serum level increases with obesity. Platelets have leptin ...

Background/aim: Leptin is a hormone that is known to be related to weight gain and obesity. The soluble leptin receptor has been found in plasma as an important determinant of leptin sensitivity. In this study, our goal ...