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Toplam kayıt 18, listelenen: 11-18
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study
(WILEY, 2018)
The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group ...
Accumulation of alpha-Synuclein in Cerebellar Purkinje Cells of Diabetic Rats and Its Potential Relationship with Inflammation and Oxidative Stress Markers
(HINDAWI PUBLISHING CORP, 2017)
Objective. The present study was conducted to evaluate the relationship between plasma oxidative stress markers such as malondialdehyde (MDA) and glutathione (GSH), inflammatory marker pentraxin-3 (PTX3), and cerebellar ...
Granulocyte colony-stimulating factor provides protection against cardiovascular autonomic neuropathy in streptozotocin-induced diabetes in rats
(ELSEVIER IRELAND LTD, 2015)
Aims: Cardiovascular autonomic neuropathy (CAN) is a relatively common and detrimental complication of diabetes mellitus (DM). Dysregulation of neuropeptides, such as calcitonin gene-related peptide (CGRP) and vasoactive ...
Neuroprotective effects of erythropoietin on Alzheimer's dementia model in rats
(WROCLAW MEDICAL UNIV, 2017)
Background. Although Alzheimer's disease (AD) is the most common age-related neurodegenerative disease and characterized by memory impairment, only symptomatic treatments are available. Objectives. Because recombinant human ...
Exenatide reduces TNF-alpha expression and improves hippocampal neuron numbers and memory in streptozotocin treated rats
(ELSEVIER SCIENCE BV, 2015)
Recent studies suggest a possible link between type 2 diabetes and Alzheimer's disease (AD). Glucoganlike peptide 1 (GLP-1) facilitates insulin release from pancreas under hyperglycemic conditions. In addition to its ...
Repeated gadoteric acid and gadobutrol exposure causes deterioration of behavior and memory functions in rats: MRI, histopathological and biochemical evidence
(Elsevier, 2021)
Gadolinium-based contrast agents (GBCAs) exert effects in different regions of the brain; however, studies on this topic are mostly focused on radiological outcomes of GBCA exposure. This paper is a preliminary attempt to ...
Exposure to hypertonic solutions during pregnancy induces autism-like behaviors via the NFAT-5 pathway in offspring in a rat model
(Pergamon-Elsevier Science Ltd, 2021)
Objectives: to investigate the effects of hyperosmolar state (HS) on immune response and inflammation via the NFAT5 pathway and examine whether immune-mediated conditions trigger autism-like behavior in offspring. Methods: ...
Modafinil Improves Autism-like Behavior in Rats by Reducing Neuroinflammation
(Springer, 2023)
To evaluate the ameliorating effect of Modafinil on neuroinflammation, behavioral, and histopathological alterations in rats induced by propionic acid (PPA). Thirty male Wistar rats were used in the study, divided into 3 ...