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Toplam kayıt 26, listelenen: 11-20
Effect of levetiracetam on hepatic fibrosis in diabetic rats
(İstanbul Bilim Üniversitesi, Tıp Fakültesi, 2015-08)
Objectives: In our study we investigated the possible effects of levetiracetam (LEV) on hepatic fibrosis in streptozotocin (STZ) induced diabetic rats with histopathology, real-time elastography imaging technique. We also ...
Fetal alkol sendromunda oksidatif stres ve antioksidan mekanizma
(İstanbul Bilim Üniversitesi, Tıp Fakültesi, 2016)
Alkol birçok organ ve dokuda (özellikle beyin ve karaciğer) doza ve kullanım süresine bağlı olarak hasar oluşturabilen bir toksindir. Doğum öncesi (prenatal) dönemde anne tarafından kullanılan alkol, fetal alkol sendromuna ...
Levetiracetam attenuates rotenone-induced toxicity: A rat model of Parkinson's disease.
(Elsevier, 2016)
Levetiracetam (LEV), a second-generation anti-epileptic drug, is used for treatment of both focal and generalized epilepsy. Growing body of evidence suggests that LEV may have neuroprotective effects. The present study was ...
Oxidative stress and cannabinoid receptor expression in type-2 diabetic rat pancreas following treatment with Δ9-THC
(Wiley Pub., 2014)
The objectives of study were (a) to determine alteration of feeding, glucose level and oxidative stress and (b) to investigate expression and localization of cannabinoid receptors in type-2 diabetic rat pancreas treated ...
Montelukast inhibits pentylenetetrazol-induced seizures in rats.
(Medical Science International, 2015)
Background: Montelukast is an antiinflammatory drug with an antioxidant property. In this study, we aimed to reveal whether montelukast has a preventive effect against seizures and post-seizure oxidative stress in ...
The cooperative effect of local angiotensin-II in liver with adriamycin hepatotoxicity on mitochondria.
(Medical Science International Publishing, 2016)
Background: Adriamycin (ADR) is a drug used clinically for anticancer treatment; however, it causes adverse effects in the liver. The mechanism by which these adverse effects occur remains unclear, impeding efforts to ...
XPD and hOGG1 gene polymorphisms in reperfusion oxidative stress
(2011)
Knee replacement surgery is an ischemia/reperfusion model, as it uses tourniquet applied to the knee area to stop the blood flow during the operation. Fifty patients that were undergoing elective arthroscopic knee surgery ...
Melatonin's effect on inflammatory cytokines in oxidative stress induced PC12 cells
(Wiley Online Library, 2013)
Introduction: Melatonin is primarily synthesized and secreted by the pineal gland. Melatonin participate in many physiological and biochemical functions. The etiology of neurodegenerative diseases has not been well understood.
The antioxidant and antiapoptotic effect of boric acid on hepatoxicity in chronic alcohol-fed rats
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2018)
The harmful use of alcohol is a worldwide problem involving all ages. This study aims to investigate chronic alcohol exposure related hepatotoxicity on the rat liver and possible hepatoprotective effects of boric acid. ...
Protective effect of edaravone against manganese-induced toxicity in cultured rat astrocytes.
(Elsevier, 2015)
Manganese (Mn), a trace metal, is essential for maintaining the normal regulation of many biochemical and cellular processes. However, accumulation of Mn due to excessive environmental exposure leads to neurological ...