Sağlık Hizmetleri Meslek Yüksekokulu

Kurumsal yönetim

2020-11-15T20:36:50Z

Kurumsal yönetim Bakkal, Elif; Aydıntuğ, Nursel Bu makalede iyi bir kurumsal yönetişim sisteminin temel prensipleri ve öğeleri tanımlanıp anlatılacaktır. Bununla birlikte iyi bir kurumsal yönetişim sisteminin bir şirkette etkin olarak nasıl işlediği ve ABD ve Avrupa’da Sağlık Hizmetleri Yönetiminde uygulanmakta olan pratikler de incelenecektir.; This paper will define and explain the key principles and elements of good corporate governance systems. It will further explain how a corporate governance framework works effectively within a company and look at effective practices for Health Care Governance in the US and Europe İstanbul Bilim Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu.

Boric acid supplementation can prevent oxidative damage caused by prenatal alcohol exposure in rat cerebral cortex

2020-11-15T12:38:00Z

Boric acid supplementation can prevent oxidative damage caused by prenatal alcohol exposure in rat cerebral cortex Savaşan Söğüt, Melis; Söğüt, İbrahim; Oğlakcı, Ayşegül; Kartkaya, Kazım; Kuşat Ol, Kevser; Kanbak, Güngör; Erden İnal, Mine Depending on its acute or chronic usage and the dosage, alcohol has toxic effects on both mother and fetus when it is administered during pregnancy 1. Up till now, fetal alcohol spectrum disorders (FASD) has been shown to include alcohol-related birth defects (ARBD), alcohol-related neurological disorders (ARND) and fetal alcohol syndrome (FAS). Children born with FAS have some difficulties in learning, memory, attention span, communication, hearing and vision. In order to overcome this problem, new strategies should be developed to prevent the teratogenic effects of alcohol on fetus. Oxidative stress has been shown to be related to many diseases including FAS 2. Oxidative stress leads to increasing lipid peroxidation and reactive oxygen species (ROS) formation that results in malfunction of the enzymes and membrane disruption 3. Antioxidants such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) have role in ROS detoxification. İstanbul Bilim Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu.

Prenatal alcohol-induced neuroapoptosis in rat brain: Protection by folic acid and betaine

2020-11-15T12:40:19Z

Prenatal alcohol-induced neuroapoptosis in rat brain: Protection by folic acid and betaine Söğüt, İbrahim; Uysal, Onur; Oğlakcı, Ayşegül; Yücel, Ferruh; Kartkaya, Kazım; Kanbak, Güngör Fetal alcohol syndrome (FAS) was first defined as mental retardation and growth deficits together with facial anomalies in newborns from chronic alcohol consumer mothers. All over the world, 1-2 out of every 1000 births are born with FAS. This ratio increases in populations with higher welfare. It is stated in many studies that prenatal alcohol consumption trigger apoptotic neurodegeneration. İstanbul Bilim Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu.

The antioxidant effect of boric acid in chronic alcohol abuse

2020-11-15T12:40:19Z

The antioxidant effect of boric acid in chronic alcohol abuse Söğüt, İbrahim; Ersöz, Melike; Paltun, Sıla Özlem; Savaşan Söğüt, Melis; Hürdağ, Canan Alcohol is a toxin that causes serious damage on many organs depending on the dose and duration of use. Chronic alcohol consumption is the most important factor that leads to cirrhosis and liver failure. In this study, oxidative stress that was generated due to chronic alcohol intake and the protective effect of boric acid was evaluated. Experimental animals were divided into four groups: control, alcohol, alcohol+boric acid and boric acid. The levels of alcohol-induced oxidative stress indicators malondialdehyde ((MDA), total sialic acid (TSA), superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)) were measured in liver tissues. While the MDA and TSA levels increased significantly in the alcohol group compared to the control group (p<0.05, p<0.01), that of the alcohol+boric acid group decreased significantly compared to the alcohol group (p<0.01, p<0.001). The TSA level was significantly low in the boric acid group as compared to the alcohol group (p<0.001). In the alcohol group, SOD and GPx activities were significantly lowered (p<0.01, p<0.001), while there was an increase in that of the alcohol + boric acid group compared to the alcohol group (p<0.01, p<0.05). SOD and GPx activities increased significantly in the boric acid group compared to the alcohol group (p<0.01, p<0.001). There was no significant difference between the groups İstanbul Bilim Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu.; İstanbul Bilim Üniversitesi, Tıp Fakültesi.; İstanbul Bilim Üniversitesi, Fen Edebiyat Fakültesi.