Yazar "Taşkın, Eylem" için Rektörlüğe Bağlı Birimler listeleme
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The cooperative effect of local angiotensin-II in liver with adriamycin hepatotoxicity on mitochondria.
Taşkın, Eylem; Güven, Celal; Şahin, Leyla; Dursun, Nurcan (Medical Science International Publishing, 2016)Background: Adriamycin (ADR) is a drug used clinically for anticancer treatment; however, it causes adverse effects in the liver. The mechanism by which these adverse effects occur remains unclear, impeding efforts to ... -
How carnosine affects cardiovascular parameters in remnant kidney model
Yapışlar, Hande; Taşkın, Eylem (2013)Puropse. Chronic kidney disease (CKD) is a majör public health concern affecting millions of people. Oxidative stress is a mediator of sytemic complications of chronic renal failure (CRF) and involved in the pathogenesis ... -
L-carnosine alters some hemorheologic and lipid peroxidation parameters in nephrectomized rats
Yapışlar, Hande; Taşkın, Eylem (Int Scientific Literature, 2014)Background: Chronic kidney disease (CKD) is a major health problem worldwide. Oxidative stress is one of the mediators of this disease. Systemic complications of oxidative stress are involved in the pathogenesis of ... -
Melatonin prevents mitochondrial damage induced by doxorubicin in mouse fibroblasts through Ampk-Ppar gamma-dependent mechanisms.
Güven, Celal; Taşkın, Eylem; Akçakaya, Handan (Medical Science International, 2016)Background: Doxorubicin (brand name: Adriamycin®) is used to treat solid tissue cancer but it also affects noncancerous tissues. Its mechanism of cytotoxicity is probably related to increased oxidation, mitochondrial ... -
The restoration of kidney mitochondria function by inhibition of angiotensin-II production in rats with acute adriamycin-induced nephrotoxicity
Taşkın, Eylem; Özdoğan, Kalender; Kindap, Elvan Kunduz; Dursun, Nurcan (Informahealthcare, 2014)Adriamycin (ADR) is commonly used for many solid tumor treatments. Its clinical utility is, however, largely limited by the adverse reactions, are known to be nephrotoxic. The mechanism by which it induces kidney damage ...