Ara
Toplam kayıt 5, listelenen: 1-5
Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1)
(Elsevier Inc, 2013)
Constitutes of the venom scorpion are a rich source of low molecular mass peptides which are toxic to various organisms, including man. Androctonus crassicauda is one of the scorpions from the Southeastern Anatolia of ...
Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK
(Elsevier, 2007)
The effect of simvastatin, a widely used statin for the treatment of hypercholesterolemia, was investigated in the estrogen receptor (ER)-positive MCF-7, and the ER-negative MDA-MB 231 human breast cancer cell lines. ...
Estradiol induces JNK-dependent apoptosis in glioblastoma cells
(Spandidos Publications, 2011)
Estrogens exert multiple regulatory actions on cellular events in a variety of tissues including the brain. In the present study, the signaling mechanisms of the concentration-dependent effects of 17-β-estradiol (estradiol) ...
Melatonin prevents mitochondrial damage induced by doxorubicin in mouse fibroblasts through Ampk-Ppar gamma-dependent mechanisms.
(Medical Science International, 2016)
Background: Doxorubicin (brand name: Adriamycin®) is used to treat solid tissue cancer but it also affects noncancerous tissues. Its mechanism of cytotoxicity is probably related to increased oxidation, mitochondrial ...
Oksitosinin hücresel tedavide kullanılma potansiyeli
(İstanbul Bilim Üniversitesi, Tıp Fakültesi, 2015-12)
Oksitosin dokuz aminoasitten oluşan bir memeli peptit hormonudur. Hipotalamusun supraoptik ve paraventriküler çekirdeklerinden sentezlenir ve beyinde nöromodülatör olarak görev alır. Bu nörotransmitterin doğum sırasında, ...