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DNA repair, cancer and cancer therapy- the current state of art
(InTech, 2011)
Over the past decades, great advances have been made in understanding the cellular DNA repair pathways. At the same time, a wealth of descriptive knowledge of human diseases has been accumulated. Now, the basic research ...
Relationship between PON1 gene Q192r polymorphism and oxidative stress of reperfusion
(The International Institute of Anticancer Research, 2011)
Background: The HDL-associated enzyme paraoxonase 1 (PON1) plays a preventive role against oxidative stress. The purpose of this study was to investigate a possible association of the PON1 Q192R polymorphism with the risk ...
XPD and hOGG1 gene polymorphisms in reperfusion oxidative stress
(2011)
Knee replacement surgery is an ischemia/reperfusion model, as it uses tourniquet applied to the knee area to stop the blood flow during the operation. Fifty patients that were undergoing elective arthroscopic knee surgery ...
MMP2 gene polymorphisms and MMP2 mRNA levels in patients with superficial varices of lower extremities
(The International Institute of Anticancer Research, 2011)
Background: Although superficial varices of the lower extremities are common and with high morbidity, their etiology has not been elucidated yet. Previously, it was thought that venous hypertension was responsible for such ...
Cox-2 gene polymorphism and IL-6 levels in coronary artery disease
(Funpec-Editora, 2011)
Coronary artery disease is one of the leading causes of mortality and diabetes mellitus is one of its main risk factors due to microvascular and macrovascular complications, such as atherosclerosis. Atherosclerosis is now ...