Yazar "Akan, Gökçe" için DBU Yayınları || DPU Publications listeleme
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11β HSD-1 and PAI-1 gene expression fructose induced metabolic syndrome rats
Akan, Gökçe; İnan, Öznur; Atalar, Fatmahan; Görmüş, Uzay; Bilir, Ayhan; Özdilli, Kürşat; Altuğ, Tuncay (2013)Backround: Metabolic syndrome (MetS) is an important health issue worldwide. It is a prevalent and complex disease, characterized by the variable coexistence of obesity, dyslipidemia, hyperinsulinaemia, and hypertension. ... -
11β-hydroxysteroid dehydrogenase type 1 gene expression is increased in ascending aorta tissue of metabolic syndrome patients with coronary artery disease
Atalar, Fatmahan; Vural, Burçak; Çiftci, Çavlan; Demirkan, Ayşe; Akan, Gökçe; Süsleyici-Duman, Belgin; Büyükdevrim, Ahmet Sevim (Genetics and Molecular Research, 2012)11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) activity and mRNA levels are increased in visceral and subcutaneous adipose tissues of metabolic syndrome subjects. We analyzed 11β-HSD-1 expression in human epicardial ... -
Association study of the DIO2 gene as a susceptibility candidate for schizophrenia in the Turkish population; A case-control study
Colak, A; Akan, Gökçe; Oncu, F; Yanbay, H; Acar, S; Yesilbursa, D; Atalar, Fatmahan (Elsevier, 2013)Introduction: Schizophrenia (SCH) is one of the major and potentially severe mental illness that is characterized by both genetic and clinical heterogeneity. Thyroid hormone plays an important role in the development of ... -
Cardiac visceral and subcutaneous adipose tissue adipokines are dysregulated in obesity and coronary artery disease
Atalar, Fatmahan; Görmez, Selçuk; Çaynak, Barış; Akan, Gökçe; Akpınar, Belhhan; Günay, Demet; Yazıcı, Zeliha (13.Ulusal Tıbbi Biyoloji ve Genetik Kongresi, 27-30 Ekim 2013, 2013)BACKGROUND: Coronary heart disease is one of the most common type of heart disease and the leading cause of mortality worldwide. A close association between obesity and increased cardiovascular diseases has been established ... -
Yüksek fruktoz diyet ile metabolik sendrom oluşturulan sıçanlarda omental yağ dokusunda glukokortikoid etkinliği ve buna bağlı olarak artan PAI-1 gen ekspresyonu
Akan, Gökçe; İnan, Öznur; Atalar, Fatmahan; Görmüş, Uzay; Bilir, Ayhan; Çiftçi, Çavlan; Altuğ, Tuncay (2013)Giriş: Metabolik sendrom (MetS) başta gelişmiş ülkeler olmak üzere tüm dünyada prevalansı giderek artan bir sağlık sorunudur. Son yıllardaki çalışmalar yüksek fruktoz tüketiminin MetS gelişiminde önemli faktörlerden biri ...