Güncel Gönderiler: DBU Yayınları || DPU Publications
Toplam kayıt 958, listelenen: 821-840
-
Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1)
(Elsevier Inc, 2013)Constitutes of the venom scorpion are a rich source of low molecular mass peptides which are toxic to various organisms, including man. Androctonus crassicauda is one of the scorpions from the Southeastern Anatolia of ... -
Stimulation of dendritic cells with vaccine and vaccine–antibody complex and effect on immune response
(TUBİTAK, 2013)Dendritic cell (DC) vaccines are a promising and potent therapeutic tool for chronic diseases, autoimmune diseases, and cancer because of the unique ability of DCs to stimulate T cells. The challenge of DC vaccines is to ... -
Kronik hepatit B’nin aşı veya aşı-antikor kompleksi ile yüklü pDC ve mDC’ler ile tedavi edilmesi
(Galenos Yayınevi, 2013)Amaç: Yapılan bu çalışmada, aşı veya aşı-antikor kompleksi ile yüklenmiş plazmasitoid dentritik hücre (pDC) ve klasik/miyeloid dentritik hücrelerinin (cDC/mDC) birbirlerine olan sinerjik etkilerinden yararlanarak kronik ... -
Event-related potentials during auditory oddball, and combined auditory oddball-visual paradigms.
(Informa Healthcare, 2007)The purpose of the current study was to investigate the properties of a new modification of the classical auditory oddball paradigm (auditory oddballparadigm combined with passive visual stimulation, AERPs + VEPs) and ... -
The effects of interstimulus interval on sensory gating and on preattentive auditory memory in the oddball paradigm. Can magnitude of the sensory gating affect preattentive auditory comparison process?
(Elsevier Inc, 2007)P50, and mismatch negativity (MMN) are components of event-related potentials (ERP) reflecting sensory gating and preattentive auditory memory, respectively. Interstimulus interval (ISI) is an important determinant of the ... -
Event-related potentials to visual, auditory, and bimodal (combined auditory-visual) stimuli.
(Informa Healthcare, 2007)The purpose of this study was to investigate the response properties of event related potentials to unimodal and bimodal stimulations. The amplitudes of N1 and P2 were larger during bimodal evoked potentials (BEPs) than ... -
The gamma-butyrolactone model of absence epilepsy: Acute and chronic effects in wistar rats
(Türk Epilepsi İle Savaş Derneği, 2013)Introduction A pharmacological modeling approach to absence epilepsy requires a reproducible and predictable method that has the EEG and behavioral characteristics of generalized typical absence seizures in humans. The ... -
Neurofeedback intervention in fibromyalgia syndrome; a randomized, controlled, rater blind clinical trial.
(Springer Link, 2010)We designed a randomized, rater blind study to assess the efficacy of EEG Biofeedback (Neurofeedback-NFB) in patients with fibromyalgia syndrome (FMS). Eighteen patients received twenty sessions of NFB-sensory motor rhythm ... -
The effect of memantine in harmaline-induced tremor and neurodegeneration
(Elsevier Inc, 2011)Essential tremor (ET) is one of the most common and most disabling movement disorders among adults. The drug treatment of ET remains unsatisfactory. Additional therapies are required for patients with inadequate response ... -
Sex-specific consequences of early life seizures
(Elsevier Inc, 2014)Seizures are very common in the early periods of life and are often associated with poor neurologic outcome in humans. Animal studies have provided evidence that early life seizures may disrupt neuronal differentiation and ... -
Perirhinal cortical kindling in rats with genetic absence epilepsy
(Elsevier Inc, 2010)Two genetic models of absence epilepsy, GAERS and WAG/Rij rat strains, are resistant to progression of partial seizures induced by amygdaloid or hippocampal kindling. Perirhinal cortex is one of the crucial areas for the ... -
Electroencephalographic differences between WAG/Rij and GAERS rat models of absence epilepsy
(Elsevier Inc, 2010)The inbred Wistar Albino Glaxo Rats from Rijswijk (WAG/Rij) and the Genetic Absence Epilepsy Rats from Strasbourg (GAERS) are well-validated genetic models of absence epilepsy. Although they share similar characteristics ... -
Effects of kindling stimulations on parvalbumin immunoreactivity in substantia nigra pars reticulata of gaers and wistar rats
(Wiley Online Library, 2014)Purpose: One of the mechanisms that control epileptic seizures involves the neural network in the substantia nigra pars reticulata (SNR). Two functionally discrete regions, SNRanterior and posterior were demonstrated to ... -
Perirhinal cortical kindling in genetic absence epilepsy rat strains
(Wiley Online Library, 2010)Purpose: The genetic models of absence epilepsy, GAERS and WAG/ Rij rat strains, are resistant to progression of partial seizures induced by amygdaloid and hippocampal kindling. Perirhinal cortex is a crucial area for the ... -
Genetik absans epilepsili WAG/RİJ sıçanlarda beynin farklı bölgelerdeki proinflamatuar sitokin düzeylerinin kinding süreciyle ilişkisi
(Türk Fizyolojik Bilimler Derneği, 2009)Epilepsi bir veya daha fazla beyin bölgelerinde tekrarlayıcı senkronize nöronal boşalımlar ile karakterize bir durumdur. Tüm epilepsiler içinde temporal lob epilepsilerinde (TLE) görülme sıklığı %30-35’dir. Kindling modeli, ... -
Memantin'in tremor şiddetini azaltıcı ve nöron koruyucu etkisi: Titreşim analizi ve immünohistokimyasal yaklaşım
(Türk Fizyolojik Bilimler Derneği, 2009)Giriş ve Amaç: Esansiyel tremor, nörodejeneratif bozukluklarda ortaya çıkan ve fonksiyonel kayba neden olan bir belirtidir (1). Harmalin, insandaki esansiyel tremora benzer şekilde, olivo-serebellar sistemin aktivitesinde ... -
Genetik absans epilepsi sıçan modelindeki kindling direncinde substansiya nigra'nın rolü
(Bilimsel Tıp, 2010)“Genetic Absence Epilepsy Rats from Strasbourg (GAERS)” ırkı sıçanlar tipik absans epilepsinin iyi tanımlanmış modellerinden biridir. Son yıllarda yapılan çalışmalarda, bu ırkın amigdale, hippokampal ve peririnal kortikal ... -
Voltaj bağımlı kalsiyum kanal α-1G altünite ekspresyonunun genetik absans epilepisili sıçanlarda değerlendirilmesi
(2011)Amaç: T tipi voltaj bağımlı kalsiyum kanalları absans epilepsy etyopatogenezinde önemli rol oynamaktadır. Talamokortikal döngü genetik absans epilepsili sıçanlarda (GAERS) diken-dalga deşarjlarının ortaya çıkmasında önemli ... -
Jeneralize absans nöbetlerin kontrolünde serebellumun rolü
(2011)Absans epilepsiler insanda ve hayvan modellerinde iyi karakterize edilmiş nöbet biçimleriyle kendini gösteren bir grup hastalıktır. EEG’de diken-dalga deşarjların (DDD) eşlik ettiği absans nöbetlerin oluşumundan, talamokortikal ... -
Genetik absans epilepsili sıçanlarda substansiya nigra ve striatumdaki dopaminerjik nöronların dansitometrik analizi
(2011)WAG/Rij ırkı sıçanlar tipik absans epilepsinin iyi tanımlanmış modellerinden biridir. Son yıllarda yapılan çalışmalarda absans epilepside dopaminerjik sistemin bozukluğunun rol oynadığı ileri sürülmektedir. Orta beyin ...
