Konu "oxidative stress" için Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed listeleme
Toplam kayıt 42, listelenen: 1-20
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Adipose-derived mesenchymal stem cells mitigate methotrexate-induced liver cirrhosis (fibrosis) model
(Verduci Editore s.r.l, 2023)OBJECTIVE: Hepatic fibrosis is a severe liver condition characterized by abnormal fibroblast activity, excessive extracellular matrix deposition, inflammation, and structural alterations. Methotrexate (MTX), a pharmaceutical ... -
Age-related changes in the activity and expression of manganese superoxide dismutase, and mitochondrial oxidant generation in female and male rats
(TURKISH BIOCHEM SOC, 2013)Objective: The aim of this study was to examine the age-and gender-related differences in peroxide production, manganese superoxide dismutase (MnSOD) activity and expression in liver mitochondria of Wistar rats at 12 and ... -
The antioxidant and antiapoptotic effect of boric acid on hepatoxicity in chronic alcohol-fed rats
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2018)The harmful use of alcohol is a worldwide problem involving all ages. This study aims to investigate chronic alcohol exposure related hepatotoxicity on the rat liver and possible hepatoprotective effects of boric acid. ... -
Chronic administration of delta9-tetrahydrocannabinol protects hyperinsulinemic gastric tissue in rats
(Wiley, 2023)Hyperinsulinemia (HI) can result from some reasons such as an increase in basal/fasting circulating insulin and/or potentiation of postprandial insulin production. Diabetes mellitus (DM) is indirectly related to HI since ... -
The cooperative effect of local angiotensin-II in liver with adriamycin hepatotoxicity on mitochondria.
(Medical Science International Publishing, 2016)Background: Adriamycin (ADR) is a drug used clinically for anticancer treatment; however, it causes adverse effects in the liver. The mechanism by which these adverse effects occur remains unclear, impeding efforts to ... -
Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology
(Turkish Association of Trauma and Emergency Surgery, 2023)BACKGROUND: Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate ... -
Effect of dietary curcumin and capsaicin on testicular and hepatic oxidant-antioxidant status in rats fed a high-fat diet
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2019)This study investigated the effects of curcumin and capsaicin on testicular and hepatic oxidant-antioxidant status in rats fed a high-fat diet (HFD). Male Sprague-Dawley rats were divided into 5 groups (8 rats per group). ... -
Effect of different storage solutions on oxidative stress in human saphenous vein grafts
(BioMed Central Ltd, 2022)Background: Ischemia–reperfusion injury of saphenous vein grafts (SVG) during coronary artery bypass grafting surgery negatively impacts endothelial integrity and functionality and is associated with vein graft failure. ... -
Effect of fulvic acid on gastric mucosa damage caused by chronic water avoidance stress
(Taylor & Francis Ltd, 2021)We investigated the antioxidant and anti-ulcerogenic effects of fulvic acid (FA) on oxidative damage caused by water avoidance stress (WAS) in rat gastrointestinal mucosa. Three experimental groups were established: control ... -
Effect of fulvic acid on gastric mucosa damage caused by chronic water avoidance stress
(Taylor and Francis Ltd., 2022)We investigated the antioxidant and anti-ulcerogenic effects of fulvic acid (FA) on oxidative damage caused by water avoidance stress (WAS) in rat gastrointestinal mucosa. Three experimental groups were established: control ... -
Effects of darbepoetin alpha on brain tissue oxidative stress in experimental ethanol administration
(Trakya Üniversitesi Tıp Fakültesi, 2009)Objectives: The hyperglycosylated erythropoietin analogue darbepoetin alpha (α) has longer half-life and higher in vivo activity. There is no data about the effects of darbepoetin-α on ethanol-induced oxidative stress. In ... -
The Effects of Fulvic Acid Against Water Avoidance Stress- Induced Damage of Rat Colon Mucosa
(Marmara Univ, Inst Health Sciences, 2023)Objective: Chronic stress plays an important role in the etiology of many inflammatory diseases. Reactive oxygen species (ROS), a source of free radicals, act as signaling molecules in the progression of stress-related ... -
Effects of Ganoderma lucidum on Obstructive Jaundice-induced Oxidative Stress
(ELSEVIER SINGAPORE PTE LTD, 2010)OBJECTIVE: Obstructive jaundice develops after occlusion of the common bile duct. Direct hyperbilirubinaemia, which occurs secondary to the condition, causes various life-threatening pathologies. Cytoprotective effects of ... -
Effects of lycopene on oxidative stress and remnant liver histology after partial hepatectomy in rats
(TURKISH SOC GASTROENTEROLOGY, 2011)Background/aims: Partial hepatectomy is performed for the treatment of mass lesions in the liver. Lycopene, which is a carotenoid, is present in various physiologic processes. In this study, the effects of lycopene ... -
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study
(WILEY, 2018)The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group ... -
EVALUATION OF OXIDATIVE STRESS IN EXPERIMENTAL ACETAMINOPHEN INDUCED HEPATOTOXICITY: EFFECTS OF DARBEPOETIN ADMINISTRATION
(NOBEL ILAC, 2010)Objective Effects of darbepoetin alfa on acetaminophen induced hepatotoxicity have been investigated by evaluating some oxidant/antioxidant parameters and liver histology Material and Method Fifty adult male Sprague Dawley ... -
Evaluation of oxidative stress markers in type-2 diabetic rat kidney with treated Delta(9)-THC
(WILEY-BLACKWELL, 2014)… -
Evaluation of the Reparative Effect of Sinomenine in an Acetaminophen-Induced Liver Injury Model
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Due to its rising global prevalence, liver failure treatments are urgently needed. Sinomenine (SIN), an alkaloid from sinomenium acutum, is being studied for its liver-repair properties due to Acetaminophen (APAP) overdose. ... -
Exenatide, a GLP-1 analog, has healing effects on LPS-induced autism model: Inflammation, oxidative stress, gliosis, cerebral GABA, and serotonin interactions
(Wiley, 2020)Previous studies have established anti-inflammatory, antioxidant, and neuroprotective effects of Exenatide in the central nervous system. Since these mechanisms are thought to have important roles in the pathophysiology ... -
Hexagonal boron nitride nanoparticles trigger oxidative stress by modulating thiol/disulfide homeostasis
(Sage Publications Ltd, 2021)Background: Hexagonal boron nitride nanoparticles (hBN NPs) are encouraging nanomaterials with unique chemical properties in medicine and biomedical fields. Until now, the optimal hBN NP's dosage and biochemical mechanism ...