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Toplam kayıt 20, listelenen: 11-20
Oxytocin mitigates peripheral nerve damage via Nrf2 and irisin pathway
(Verduci Editore s.r.l, 2023)
OBJECTIVE: Peripheral nerve injuries present challenges in achieving full functional restoration, necessitating effective therapeutic strategies. Oxytocin, known for its neuroprotective and anti-inflammatory properties, ...
Assessment of Apparent Diffusion Coefficient Parameters and Coefficient of Variance in Discrimination of Receptor Status and Molecular Subtypes of Breast Cancer
(Bentham Science Publishers, 2024)
Objective: The objective of this study was to investigate the diagnostic power of apparent diffusion coefficient/coefficient of variance (ADCcV) as well as ADC parameters formed based on magnetic resonance images (MRI) in ...
The neuro-restorative effect of adipose-derived mesenchymal stem cell transplantation on a mouse model of diabetic neuropathy
(Taylor and Francis Ltd., 2022)
Diabetic neuropathy (DN) is the most common degenerative complication associated with Diabetes Mellitus. Despite widespread awareness about DN, the only effective treatments are blood glucose control and pain management. ...
The Efficacy of Hydrodilatation for the Prevention of Vasospasm following Microsurgical Anastomosis
(Thieme Medical Publishers, Inc., 2022)
Background âVasospasm is a major problem following microsurgical reconstruction which can result in the partial or complete loss of the flap tissue. The aim of this study was to investigate the efficiency of hydrodilatation ...
The Effect of Liraglutide on Axon Regeneration and Functional Recovery after Peripheral Nerve Lesion
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)
Peripheral nerve injuries inflict severe consequences, necessitating innovative therapeutic strategies. This study investigates the potential of liraglutide, a glucagon-like peptide-1 receptor agonist, in mitigating the ...
Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology
(Turkish Association of Trauma and Emergency Surgery, 2023)
BACKGROUND: Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate ...
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats
(Taylor and Francis Ltd., 2022)
Aim: Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ...
Hepatic insulin synthesis increases in rat models of diabetes mellitus type 1 and 2 differently
(Public Library of Science, 2023)
Insulin-positive (+) cells (IPCs), detected in multiple organs, are of great interest as a probable alternative to ameliorate pancreatic beta-cells dysfunction and insulin deficiency in diabetes. Liver is a potential source ...
COSMC expression as a predictor of remission in IgA nephropathy
(Springer Science and Business Media B.V., 2023)
Purpose: The impact of core 1,3-galactosyltransferase-specific molecular chaperon (COSMC) gene expression and methylation profile on clinical progression of IgA nephropathy (IgAN) is unclear. The aim of this study was to ...
Adipose-derived mesenchymal stem cells mitigate methotrexate-induced liver cirrhosis (fibrosis) model
(Verduci Editore s.r.l, 2023)
OBJECTIVE: Hepatic fibrosis is a severe liver condition characterized by abnormal fibroblast activity, excessive extracellular matrix deposition, inflammation, and structural alterations. Methotrexate (MTX), a pharmaceutical ...