Ara
Toplam kayıt 35, listelenen: 11-20
The Impact of Hybrid Capture-Based Comprehensive Genomic Profiling on Treatment Strategies in Patients with Solid Tumors
(Turkiye Klinikleri, 2022)
Objective: The development of bioinformatics and comprehensive genomic profiling (CGP) has provided insights into the ap-plicability and functionality of the genomic alterations (GA). In this study, we evaluated the impact ...
Distribution of HLA epitope frequencies in Turkish population
(De Gruyter Open Ltd, 2022)
Objectives: The antibodies interact with the “Human Leukocyte Antigen (HLA) antigens” at specific epitopes. “Epitopes” are present on a single HLA or shared by multiple antigens. In this study, we aim to determine the ...
Evaluation of Predisposing Metabolic Risk Factors for Portopulmonary Hypertension in Patients with NASH Cirrhosis
(Dove Medical Press Ltd, 2022)
Purpose: Metabolic parameters are important for the development of portopulmonary hypertension (PoPH) during nonalcoholic steatohepatitis (NASH)-associated cirrhosis. This study evaluated patients with NASH-associated ...
Endothelial Activation and Stress Index (EASIX) to predict mortality after allogeneic stem cell transplantation: A prospective study
(BMJ Publishing Group, 2024)
Background We previously reported that the "Endothelial Activation and Stress Index"(EASIX; ((creatinine×lactate dehydrogenase)÷thrombocytes)) measured before start of conditioning predicts mortality after allogeneic ...
Beneficial effects of sennoside B on pentylenetetrazole-induced seizures in rats
(SAGE Publications Ltd, 2023)
Background: Epilepsy is a common disorder affecting approximately 50 million people worldwide. Oxidative stress is known to play an important role in the pathophysiology of diseases, including epilepsy. In this study, we ...
Burkitt lymphoma with a granulomatous reaction: an M1/Th1-polarised microenvironment is associated with controlled growth and spontaneous regression
(John Wiley and Sons Inc, 2022)
Aims: Burkitt lymphoma (BL) is an aggressive B-cell lymphoma that, in some instances, may show a granulomatous reaction associated with a favourable prognosis and occasional spontaneous regression. In the present study, ...
Short-term protective effect of octreotide on the lungs of rats with experimentally induced sepsis
(Turkish Association of Trauma and Emergency Surgery, 2022)
BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ...
Evaluation of the Reparative Effect of Sinomenine in an Acetaminophen-Induced Liver Injury Model
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)
Due to its rising global prevalence, liver failure treatments are urgently needed. Sinomenine (SIN), an alkaloid from sinomenium acutum, is being studied for its liver-repair properties due to Acetaminophen (APAP) overdose. ...
The relationship between clinical parameters and hepatocyte growth factor/c-Met levels in the sperm of infertile males
(IMR Press Limited, 2022)
Objective: Hepatocyte growth factor is a pleiotropic cytokine with potent mitogenic activity in many organs and tissues. The receptor for hepatocyte growth factor is c-Met, a transmembrane glycoprotein with tyrosine kinase ...
PET/MR and Its Applications in Radiotherapy
(Galenos Publishing House, 2023)
Modern radiotherapy applications such as dose staining and intensity-modulated radiotherapy require diagnostic images that can offer good resolution and high soft tissue contrast. The combination of positron emission ...