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Toplam kayıt 34, listelenen: 1-10
Neuroprotective Effects of Eexenatide in a Rotenone-Induced Rat Model of Parkinson's Disease
(ELSEVIER SCIENCE INC, 2017)
Backround: Several studies suggest an association between Parkinson's disease (PD) and type 2 diabetes mellitus; these 2 diseases are both known to affect the common molecular pathways. As a synthetic agonist for the ...
Antipsychotic Like Effects of Atorvastatin and Melatonin in a Psychosis Model in Rats
(YERKURE TANITIM & YAYINCILIK HIZMETLERI A S, 2015)
Objective: In recent years besides dopaminergic imbalance exhibition of other possible mechanisms like inflammation and serotonergic abnormalities have pointed out the need for new antipsychotic drugs. In this study our ...
Silymarin ameliorates uterine and ovarian damage in streptozotocin induced diabetic rat model
(NATL INST SCIENCE COMMUNICATION-NISCAIR, 2018)
Diabetes is a systemic disease that affects microvasculature in almost all organs. Uterus and the ovaries may also be a target for diabetes. We investigated effects of diabetes on the uterus and the ovaries and the role ...
The Protective Role of Resveratrol on Diabetic Cardiomyopathy in Streptozocin Induced Diabetic Rats
(2019)
Objectives: We aimed to investigate the effect of resveratrol on diabetic cardiomyopathy in streptozocininduced diabetic rats. Materials and Methods: Rats were injected with streptozocin to establish diabetes model. After ...
Therapeutic effect of adenosine on experimentally induced acute ulcerative colitis model in rats
(Acta Cirurgica Brasileira, 2019)
Purpose: To examine the therapeutic effect of external adenosine on an acetic acid-induced acute ulcerative colitis model in rats. Methods: Thirty male mature rats were divided into three groups as control, acute colitis ...
Pentilentetrazol ile oluşturulan konvülziyon modelinde metilen mavisi ve tadalafilin etkileri
(2016)
L-Arjinin (L-ARG) -nitrik oksid (NO) -cGMP (siklik guanozin monofosfat) döngüsünün epilepsideki rolünü gösteren bazı çalışmalar vardır. Tadalafil, fosfodiesteraz-5 (PDE5) 'in güçlü bir inhibitörüdür ve cGMP'nin etkisini ...
The reducing effect of agomelatine on pentylenetetrazol-induced convulsions
(Akademiai Kiado Zrt, 2019)
Introduction: Agomelatine is a potent MT1 and MT2 melatonin receptor agonist and a 5-HT2C serotonin receptor antagonist. the purpose of this study was to show the convulsion-reducing effect of agomelatine, in both clinical ...
Highly selective SGLT2 inhibitor dapagliflozin reduces seizure activity in pentylenetetrazol-induced murine model of epilepsy
(BIOMED CENTRAL LTD, 2018)
Background: Worldwide, over 10 million individuals suffer from drug-resistant epilepsy. New therapeutic strategies are needed to address this debilitating disease. Inhibition of sodium-glucose linked transporters (SGLTs), ...
Effect of platelet-rich plasma on reconstruction with nerve autografts
(ELSEVIER TAIWAN, 2017)
Despite advances in understanding of peripheral nerve injuries and regeneration and advances in surgical techniques, successful outcomes cannot be guaranteed after reconstructive surgery. Platelet-rich plasma (PRP) has ...
The efficacy of Aesculus hippocastanum seeds on diabetic nephropathy in a streptozotocin-induced diabetic rat model
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2016)
Cytokines, such as transforming growth factor (TGF)-beta 1, and increased oxidative stress are considered to be responsible for the development of diabetic nephropathy. We hypothesized that Aesculus hippocastanum (AH) seeds ...