Güncel Gönderiler: Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed
Toplam kayıt 3635, listelenen: 261-280
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Effect of Voltage-Gated Sodium Channel Inhibitors on the Metastatic Behavior of Prostate Cancer Cells: A Meta-Analysis
(Asian Network for Scientific Information, 2023)Background and Objective: Functional Voltage-Gated Sodium Channels (VGSCs) are expressed in metastatic prostate cancer (PCa) cells. A number of in vitro studies have evaluated the effect of functional VGSC expression on ... -
Vitamins C and E protect from sepsis-induced lung damage in rat and CT correlation
(Comenius University in Bratislava, 2022)BACKGROUND: Sepsis is one of the leading causes of death in intensive care units worldwide. Vitamins C and E are natural antioxidants and anti-infl ammatory agents. Suppressing the infl ammation is an important treatment ... -
One-Third of European Patients With Axial Spondyloarthritis Reach Pain Remission With Routine Care Tumor Necrosis Factor Inhibitor Treatment
(Journal of Rheumatology, 2023)Objective. To investigate the distribution of patient-reported outcomes (PROs) in patients with axial spondyloarthritis (axSpA) initiating a tumor necrosis factor inhibitor (TNFi), to assess the proportion reaching PRO ... -
Evaluation of the Reparative Effect of Sinomenine in an Acetaminophen-Induced Liver Injury Model
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Due to its rising global prevalence, liver failure treatments are urgently needed. Sinomenine (SIN), an alkaloid from sinomenium acutum, is being studied for its liver-repair properties due to Acetaminophen (APAP) overdose. ... -
THE EVALUATION OF AWARENESS AND LEVEL OF KNOWLEDGE RELATED TO TUBERCULOSIS OF PHARMACY FACULTY STUDENTS: A FOUNDATION UNIVERSITY EXAMPLE
(University of Ankara, 2022)Objective: Tuberculosis (TB) is an infectious disease that is among the leading causes of death. TB can easily spread by aerosols from pulmonary TB patients. Pharmacists are unique among healthcare professionals because ... -
The Effect of Liraglutide on Axon Regeneration and Functional Recovery after Peripheral Nerve Lesion
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Peripheral nerve injuries inflict severe consequences, necessitating innovative therapeutic strategies. This study investigates the potential of liraglutide, a glucagon-like peptide-1 receptor agonist, in mitigating the ... -
Metronomic Temozolomide (mTMZ) and Bevacizumab—The Safe and Effective Frontier for Treating Metastatic Neuroendocrine Tumors (NETs): A Single-Center Experience
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Addressing the persistent challenges in treating metastatic neuroendocrine tumors (NETs) demands ongoing refinement and innovation in therapeutic strategies. This study investigates the potential advantages of combining ... -
Microsurgical anatomy of the auditory radiations: revealing the enigmatic acoustic pathway from a surgical viewpoint
(American Association of Neurological Surgeons, 2023)OBJECTIVE The thalamocortical projections of the auditory system have not been detailed via microanatomical fiber dissections from a surgical viewpoint. The aim of this study was to delineate the course of the auditory ... -
Stem Cell Mobilization Efficiency and Engraftment Kinetics in Patients with Hematologic Malignancies Undergoing Autologous Stem Cell Transplantation: A Retrospective Cohort Study*
(Istanbul University Press, 2023)Objective: This study aimed to conduct a retrospective evaluation of clinical findings on patients undergoing autologous hematopoietic stem cell transplantation. Materials and Methods: A total of 167 consecutive patients ... -
Assessment of Apparent Diffusion Coefficient Parameters and Coefficient of Variance in Discrimination of Receptor Status and Molecular Subtypes of Breast Cancer
(Bentham Science Publishers, 2024)Objective: The objective of this study was to investigate the diagnostic power of apparent diffusion coefficient/coefficient of variance (ADCcV) as well as ADC parameters formed based on magnetic resonance images (MRI) in ... -
Total Antioxidant Potential, Total Phenolic Profile and Cytotoxic Activity Against Brain Cancer: Melocan and Galdirik
(University of Zagreb, 2023)Research background. Brain cancer is known to be one of the most difficult types of cancer to cure. It has a serious impact on the lives of diagnosed people due to the insufficient treatment options and their side effects. ... -
Adipose-derived mesenchymal stem cells mitigate methotrexate-induced liver cirrhosis (fibrosis) model
(Verduci Editore s.r.l, 2023)OBJECTIVE: Hepatic fibrosis is a severe liver condition characterized by abnormal fibroblast activity, excessive extracellular matrix deposition, inflammation, and structural alterations. Methotrexate (MTX), a pharmaceutical ... -
Oxytocin mitigates peripheral nerve damage via Nrf2 and irisin pathway
(Verduci Editore s.r.l, 2023)OBJECTIVE: Peripheral nerve injuries present challenges in achieving full functional restoration, necessitating effective therapeutic strategies. Oxytocin, known for its neuroprotective and anti-inflammatory properties, ... -
An Approach to Non-left Main Bifurcation Lesions: A Contemporary Review
(Radcliffe Medical Media, 2023)Bifurcated anatomical locations in the arterial tree, such as coronary artery bifurcations, are prone to develop obstructive atherosclerotic lesions due to the pro-atherogenic low wall shear stress. The percutaneous treatment ... -
Thiol/disulfide homeostasis and oxidant status in children with congenital heart disease
(De Gruyter Open Ltd, 2022)Objectives: This article aims to explain the altered oxidative status and thiol/disulfide homeostasis before and after surgery in children with congenital heart disease (CHD). Methods: Blood samples were taken from the ... -
Neuroprotective and metabotropic effect of aerobic exercise training in female patients with type 2 diabetes mellitus
(De Gruyter Open Ltd, 2022)We aimed to evaluate the effects of acute and chronic aerobic exercise on cognitive function and depression levels in patients with Type 2 Diabetes Mellitus (T2DM) and the changes in related neurotrophic and metabotropic ... -
Assessment of biventricular myocardial systolic function in COVID-19 patients: A Tissue Doppler Imaging echocardiography study
(Akademiai Kiado ZRt., 2023)Background: The 2019 novel coronavirus disease (COVID-19) has been reported as pandemy and the number of patients continues to rise. Based on recent data, cardiac injury is a prominent feature of the disease, leading to ... -
Factor 5 and Factor 2 heterozygous positivity and complications in living donor liver transplant donors
(Kare Publishing, 2023)OBJECTIVE: Factor 2 and Factor 5 mutations are among the most common procoagulant genetic disorders and are routinely evaluated in donor preparation. Homozygous mutations are contraindicated for surgery, but heterozygous ... -
Short-term protective effect of octreotide on the lungs of rats with experimentally induced sepsis
(Turkish Association of Trauma and Emergency Surgery, 2022)BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ... -
Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology
(Turkish Association of Trauma and Emergency Surgery, 2023)BACKGROUND: Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate ...
