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Toplam kayıt 1427, listelenen: 61-80
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Anti-inflammatory potential of delta-9-tetrahydrocannabinol in hyperinsulinemia: an experimental study
(Springer, 2022)Background Hyperinsulinemia (HI) means that the amount of insulin in the blood is higher than normal and is often associated with type 2 diabetes. It is known that delta-9-tetrahydrocannabinol (THC) obtained from a medicinal ... -
Anti-Proliferative and Apoptotic Effects of Methanolic Extracts from Different Cladonia Species on Human Breast Cancer Cells
(CHARLES UNIV PRAGUE, FIRST FACULTY MEDICINE, 2015)This study tries to elucidate the anti-proliferative and apoptotic effects of methanolic lichen extracts from Cladonia rangiformis and Cladonia convolute in MCF-7 human breast cancer cells. Lichen extracts (0-2 mg/ml) were ... -
Anti-seizure effect of zinc on PTZ-induced epilepsy in rat model
(Aepress Sro, 2022)Epilepsy is a widespread and mainly severe neurological condition portrayed by recurring spontaneous seizures caused by the brain's abnormal electrical activity. According to new research, inflammation may be both a result ... -
Anticonvulsant activity of 3,5-dimethylpyrazole derivatives in animal models
(BIRKHAUSER BOSTON INC, 2011)A series of 3,5-dimethylpyrazole derivatives, structurally related to the previously described potent ameltolide analogues, were synthesized and evaluated for their anticonvulsant activity. Ten compounds were prepared by ... -
Antifibrotic Effect of Lactulose on a Methotrexate-Induced Liver Injury Model
(HINDAWI LTD, 2017)The most severe side effect of prolonged MTX treatment is hepatotoxicity. The aim of this study is to investigate the effect of lactulose treatment on MTX-induced hepatotoxicity in a rat model. Twenty-four male rats were ... -
Antifibrotic preventive effect of polyethylene glycol (PEG) 3350 in methotrexate-induced hepatoxicity model
(Acta Cirurgica Brasileira, 2022)Purpose: Liver damage caused by drugs and other chemicals accounts for about 5% of all cases. Methotrexate (MTX), a folic acid analogue, is a first-line synthetic antimetabolite agent routinely used in the treatment of ... -
The antioxidant and antiapoptotic effect of boric acid on hepatoxicity in chronic alcohol-fed rats
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2018)The harmful use of alcohol is a worldwide problem involving all ages. This study aims to investigate chronic alcohol exposure related hepatotoxicity on the rat liver and possible hepatoprotective effects of boric acid. ... -
Antioxidant effect of carnosine treatment on renal oxidative stress in streptozotocin-induced diabetic rats.
(Taylor and Francis Online, 2014)Nitric oxide (NO) plays a significant role in the development of diabetic nephropathy. We investigated the effects of an antioxidant, carnosine, on streptozotocin (STZ)-induced renal injury in diabetic rats. We used four ... -
The antioxidant role of agomelatine and gallic acid on oxidative stress in STZ induced type I diabetic rat testes
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017)Diabetes is a multisystem disorder and its effects are observed on the reproductive system. One of the main causes of testicular tissue damage is diabetes-induced overproduction of reactive oxygen species and glycated end ... -
Antipsychotic Like Effects of Atorvastatin and Melatonin in a Psychosis Model in Rats
(YERKURE TANITIM & YAYINCILIK HIZMETLERI A S, 2015)Objective: In recent years besides dopaminergic imbalance exhibition of other possible mechanisms like inflammation and serotonergic abnormalities have pointed out the need for new antipsychotic drugs. In this study our ... -
Antipsychotic-like effect of agomelatine in a rodent model
(Yerküre Tanıtım ve Yayıncılık Hizmetleri, 2015)Objective: Agomelatine is a naphthalene bioisostere of melatonin. Melatonin is involved in several neurophysiological systems; nevertheless, data about the relationship between melatonin and psychosis such as schizophrenia ... -
An antiquated contraindication for minimally invasive lung surgery: No place to staple the bronchus
(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2019)Background: This study aims to evaluate the feasibility and outcomes of lobectomy operations without using a stapler for bronchial closure. Methods: Between December 2014 and August 2018, a total of 108 patients (72 males, ... -
Anxiety and depression predict quality of life in Turkish patients with systemic lupus erythematosus
(CLINICAL & EXPER RHEUMATOLOGY, 2015)Objective The aim of our study was to evaluate quality of life (QoL) in patients with systemic lupus erythematosus (SLE) and assess the impact of disease activity and psychological distress on health-related quality of ... -
Apolipoprotein E Genotypes in Patients with Prostate Cancer
(INT INST ANTICANCER RESEARCH, 2016)Background: Apolipoprotein E (ApoE) is a potential inhibitor of cell proliferation, immune regulation and modulation of cell growth and differentiation; it also has a substantial role in antioxidant activity. ApoE has a ... -
Appetite-regulating Hormones in Chronic Kidney Disease Patients
(W B SAUNDERS CO-ELSEVIER INC, 2011)Objective: Inflammation and loss of appetite is the most common problem in patients with chronic kidney disease (CKD). This comparative cross-sectional study aimed to characterize the changes in circulating levels of ... -
The Application of Positron Emission Tomography/Computed Tomography in Radiation Treatment Planning: Effect on Gross Target Volume Definition and Treatment Management
(ELSEVIER SCIENCE LONDON, 2010)Aims: To analyse the effect of the use of molecular imaging on gross target volume (GTV) definition and treatment management. Materials and methods: Fifty patients with various solid tumours who underwent positron emission ... -
An Approach to Conversion Disorder with Comorbid Major Depression Using Pharmacotherapy and Psychodrama Techniques: A Case Report
(YERKURE TANITIM & YAYINCILIK HIZMETLERI A S, 2018)Conversion disorder (CD) is a psychiatric disorder commonly seen in clinical and emergency psychiatry departments; it may occur with psychological factors and lead to changes in motor and sensory functioning in a way that ... -
Appropriate neck circumference cut-off points for metabolic syndrome in Turkish patients with type 2 diabetes
(ELSEVIER SCIENCE BV, 2017)Objective: To investigate the association between neck circumference (NC), overweight, and metabolic syndrome (MS) in Turkish patients with type 2 diabetes. Methods: A total of 264 diabetic patients (mean age: 52.9 +/- 8.1 ... -
Appropriate Neck Circumference Cut-Off Points for Overweight and Central Obesity In Turkish University Students
(Mattioli 1885, 2021)Background: NC is an easier and faster anthropometric measurement and has been demonstrated that there is strong correlation between NC and WC Material and Methods: In addition to our preliminary study we have demonstrated ... -
ARE C-REACTIVE PROTEIN AND PROCALCITONIN EFFECTIVE BIOMARKERS FOR URINARY TRACT INFECTION IN ELDERLY PATIENTS? WHAT SHOULD BE ADMINISTERED FOR EMPIRICIAL TREATMENT?
(Turkish Geriatrics Soc, 2023)Introduction: In the absence of typical overt symptoms, diagnosis of urinary tract infection is more difficult in elderly individuals. This study investigated the benefits of C-reactive protein, procalcitonin, and leukocyte ...