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Toplam kayıt 89, listelenen: 11-20
Preventive effect of trimetazidine against ischemia-reperfusion injury in rat epigastric island flaps: an experimental study
Background For plastic surgery, ischemia-reperfusion (I-R) injury is a critical problem that results in partial or total flap necrosis. Trimetazidine (TMZ) is a drug used in the treatment of angina pectoris. This study ...
Therapeutic effects of vitamin D on acetic acid-induced colitis in rats
(Acta Cirurgica Brasileira, 2020)
Purpose: To analyze the effect of calcitriol treatment on acute colitis in an experimental rat model. Methods: A total of 24 adult Sprague Dawley albino rats were randomly separated into 3 equal groups: control group (n:8), ...
The Ameliorative Effects of Ascorbic Acid on Critical Illness Polyneuropathy in Rodent Sepsis Model
(Georg Thieme Verlag Kg, 2020)
Although the exact pathophysiology of critical illness polyneuropathy (CIP) is still unknown, there are several hypotheses, some of which are increased inflammation and oxidative stress. We used rodent sepsis model in which ...
Tadalafil attenuates ischemic damage as well as reperfusion injury in the rat ovary
(Galenos Yayincilik, 2020)
Objective: Tadalafil is a selective phosphodiesterase type-5 inhibitor with a long half-life. It has a dual function in ischaemic and re-perfused tissues, i.e. vasodilatation and anti-oxidant effects. These features of ...
Losartan ameliorates ovarian ischaemia/reperfusion injury in rats: an experimental study
(Taylor & Francis Inc, 2020)
This study aimed to investigate the protective and antioxidant role of losartan in ovarian ischaemia and ischaemia/reperfusion injury in an experimental ovarian torsion model. Thirty adult female rats were used. Rats were ...
Papaverine Has Therapeutic Potential for Sepsis-Induced Neuropathy in Rats, Possibly via the Modulation of HMGB1-RAGE Axis and Its Antioxidant Prosperities
Aim Our aim was to investigate the possible neuroprotective properties of papaverine in sepsis-induced critical illness neuropathy (SCIN) through the evaluation of various inflammatory biochemical markers, including ...
Therapeutic effect of adenosine on experimentally induced acute ulcerative colitis model in rats
(Acta Cirurgica Brasileira, 2019)
Purpose: To examine the therapeutic effect of external adenosine on an acetic acid-induced acute ulcerative colitis model in rats. Methods: Thirty male mature rats were divided into three groups as control, acute colitis ...
Beneficial Effects of Ibuprofen on Pentylenetetrazol-induced Convulsion
(Springer/Plenum Publishers, 2020)
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used as an anti-inflammatory, anti-pyretic, and analgesic. Although some studies have focused on the anti-inflammatory and anti-pyretic properties ...
The investigation of therapeutic potential of oxytocin and liraglutide on vincristine-induced neuropathy in rats
(Wiley, 2020)
The aim of this study was to assess the therapeutic potential of oxytocin and liraglutide (LIR), a GLP-1 analogue, in a rat model of vincristine-induced neuropathy. Rats were injected with vincristine (VCR) at a dose of 4 ...
The Role of Ankaferd Blood Stopper and Oxytocin as Potential Therapeutic Agents in Endometriosis: A Rat Model
(Springer, 2020)
To evaluate the potential effect of Ankaferd Blood Stopper (ABS) and oxytocin (OT) in an experimental endometriosis model, 18 female Sprague Dawley rats were used in this study. the animals were divided randomly into three ...