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Toplam kayıt 804, listelenen: 781-790
Clinical and genetic analyses in syndromic intellectual disability with primary microcephaly reveal biallelic and de novo variants in patients with parental consanguinity
(Springer, 2023)
Background Syndromic intellectual disability (ID) with accompanying primary microcephaly is a group of rare neurodevelopmental disorders exhibiting extreme genetic and clinical heterogeneity. This layered heterogeneity can ...
Investigation of the effect of breathing exercise on invasive pain associated with arteriovenous fistula cannulation in hemodialysis patients: Randomized controlled, single-blind study
(Sage Publications Ltd, 2023)
Background: Pain due to puncture during arteriovenous fistula (AVF) cannulation is a very important symptom that affects the quality of life in patients undergoing continuous hemodialysis (HD) therapy. The aim in this study ...
Comparison of Functional Outcomes and Complications of Inlay and Onlay Reverse Shoulder Arthroplasty in Neer Type 4 Proximal Humerus Fractures and Cuff Tear Arthropathy: A Multicentric Study
(Springer Heidelberg, 2024)
Background This multicenter retrospective study was conducted with the objective of comparing the outcomes and complications between inlay and onlay reverse shoulder arthroplasty (RSA) in patients presenting Neer Type 4 ...
Digoxin Exhibits Neuroprotective Properties in a Rat Model of Dementia
(Springer/Plenum Publishers, 2022)
Alzheimer's disease (AD) is by far the most common cause of cognitive impairment in older adults. Current treatments are entirely focused on the symptoms of AD. A complex etiology for AD has been proposed recently, in which ...
The role of cytokines and T-bet, GATA3, ROR-?t, and FOXP3 transcription factors of T cell subsets in the natural clinical progression of Type 1 Diabetes
(Springer, 2023)
Th cells play an important role in pathogenesis of type 1 diabetes (T1D). Peripheral blood mononuclear cells were isolated from peripheral blood samples from newly diagnosed (ND), 1-year (1YD), and 5-year T1D (5YD) patients ...
An Investigation into the Protective Effects of Various Doses of Boric Acid on Liver, Kidney, and Brain Tissue Damage Caused by High Levels of Acute Alcohol Consumption
(Springernature, 2023)
Acute high-dose alcohol consumption can lead to oxidative stress, which can cause harm to organs. In this study we aim to determine whether administering boric acid (BA) can protect certain organs (liver, kidney, and brain) ...
Investigation of the neuroprotective effect of Granisetron through SV2A and 5-HT3 modulation in a radiation-induced brain injury rat model
(Ijrr-Iranian Journal Radiation Res, 2023)
Background: The development of neurotoxicity in healthy, non-targeted brain tissue exposed to radiation during cranial radiotherapy (RT) is the most frequent event of radiation-induced adverse effects. The 5-hydroxytryptamine-3 ...
Protective Effects of Ibudilast Against Cisplatin-Induced Hepatotoxicity and Nephrotoxicity Mediated by Prostacyclin Enhancement
(Asian Network Scientific Information-Ansinet, 2023)
Background and Objective: Cisplatin, a prevalent chemotherapy drug, presents hepatotoxic and nephrotoxic side effects, this study explores ibudilast's potential protective effects against such damage via prostacyclin ...
Endovascular treatment of posterior circulation aneurysms: Results from a single-team experience of 81 cases including 13 flow diversion treatment
(Elsevier Espana Slu, 2023)
Introduction: Relatively constant surgical risks and rapid advances in endovascular treatment have caused a major shift toward endovascular management of posterior circulation aneurysms. This paper presents the results of ...
Chronic administration of delta9-tetrahydrocannabinol protects hyperinsulinemic gastric tissue in rats
(Wiley, 2023)
Hyperinsulinemia (HI) can result from some reasons such as an increase in basal/fasting circulating insulin and/or potentiation of postprandial insulin production. Diabetes mellitus (DM) is indirectly related to HI since ...