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Toplam kayıt 7, listelenen: 1-7
Short term protective effect of digitoxin in sepsis-induced acute lung injury
(Tech Science Press, 2022)
Purpose: Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known antiinflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light ...
Vitamin C (Ascorbic acid) protects from neuropathy caused by cisplatin, through enhanced heat shock protein-70 and reduced oxidant effect
(Assoc Medica Brasileira, 2022)
OBJECTIVE: We aimed to determine whether vitamin C has a protective effect on cisplatin-induced neuropathy in rats.METHODS: In total, 24 rats were included in the study of which 8 rats (no drug administered) were categorized ...
Antifibrotic preventive effect of polyethylene glycol (PEG) 3350 in methotrexate-induced hepatoxicity model
(Acta Cirurgica Brasileira, 2022)
Purpose: Liver damage caused by drugs and other chemicals accounts for about 5% of all cases. Methotrexate (MTX), a folic acid analogue, is a first-line synthetic antimetabolite agent routinely used in the treatment of ...
The effect of Madopar on absence-like seizures in WAG/Rij rats
(Nencki Inst Experimental Biology, 2022)
The aim of this study was to investigate the effect of Madopar on the absence seizures and the anxiety-like behavior (assessed using the open field test) in Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats. Twenty-eight male ...
Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model
(Acta Cirurgica Brasileira, 2022)
Purpose: To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats. Methods: Thirty male Wistar albino rats were used. Rats were randomly divided into three equal groups, and ...
Short term protective effect of digitoxin in sepsis-induced acute lung injury
(Tech Science Press, 2022)
Purpose: Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known antiinflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light ...
Ameliorating Effect of Propofol on Cisplatin -Induced Liver and Kidney Damage in Rats
(Asian Network Scientific Information-Ansinet, 2022)
Background and Objective: Cisplatin is among the most frequently used in solid organ cancers. However, it can be dose-limiting, especially due to its side effects on the kidney and liver. This study aims to examine the ...