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Toplam kayıt 11, listelenen: 1-10
Epileptic seizures in cerebral venous sinus thrombosis: Subgroup analysis of VENOST study
(W B Saunders Co Ltd, 2020)
Purpose: the aim of this study is to evaluate the presence and prognostic impact of early seizures in cerebral venous sinus thrombosis patients (CVST). Method: VENOST is a retrospective and prospective national multicenter ...
The potential effects of anticonvulsant drugs on neuropeptides and neurotrophins in pentylenetetrazol kindled seizures in the rat
(Taylor & Francis Ltd, 2020)
Purpose: Neuropeptides and neurotrophic factors are thought to be involved in epileptogenesis. This study aims to investigate the potential effects of anticonvulsant drugs on neuropeptides (galanin and neuropeptide Y) and ...
Beneficial Effects of Ibuprofen on Pentylenetetrazol-induced Convulsion
(Springer/Plenum Publishers, 2020)
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used as an anti-inflammatory, anti-pyretic, and analgesic. Although some studies have focused on the anti-inflammatory and anti-pyretic properties ...
Effects of the Calcium Channel Blocker Otilonium Bromide on Seizure Activity in Rats With Pentylenetetrazole-Induced Convulsions
(Springer/Plenum Publishers, 2021)
Millions of people suffer from drug-resistant epilepsy. New therapeutic approaches for removing this life-affecting disease are required. The activation of T-type calcium channels (TTCC) is one of the epileptogenesis ...
The effect of sulfasalazine in pentylenetetrazole-induced seizures in rats
(Assoc Bras Divulg Cientifica, 2021)
We aimed to reveal the anti-convulsant effects sulfasalazine and its mechanism in pentylenetetrazole (PTZ)-induced seizures in rats. Forty-eight male Wistar albino rats (200-250 g) were randomly divided into two groups: ...
The effect of Madopar on absence-like seizures in WAG/Rij rats
(Nencki Inst Experimental Biology, 2022)
The aim of this study was to investigate the effect of Madopar on the absence seizures and the anxiety-like behavior (assessed using the open field test) in Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats. Twenty-eight male ...
Research Article Nasal Oxytocin's Anticonvulsant Effects on Pentylenetetrazolinduced Convulsions in Rats
(Asian Network Scientific Information-Ansinet, 2023)
Background and Objective: Neurodegenerative proteins and pro-inflammatory mechanisms may cause epilepsy through excitatory-inhibitory imbalance. Drug resistance is common, therefore this disease requires affordable, ...
N-acetyl cysteine: A new look at its effect on PTZ-induced convulsions
(Elsevier, 2023)
Introduction/Aim: Epilepsy is widely investigated as a common neurological disease requiring pharmacologically effective agents. N-acetyl cysteine (NAC), has become a remarkable molecule with its role in both antioxidant ...
Immunosuppressant Tacrolimus Treatment Delays Acute Seizure Occurrence, Reduces Elevated Oxidative Stress, and Reverses PGF2? Burst in the Brain of PTZ-Treated Rats
(Springer/Plenum Publishers, 2023)
It is still an urgent need to find alternative and effective therapies to combat epileptic seizures. Tacrolimus as a potent immunosuppressant and calcineurin inhibitor is emerging as promising drug to suppress seizures. ...
Prolongation of absence seizures and changes in serotonergic and dopaminergic neurotransmission by nigrostriatal pathway degeneration in genetic absence epilepsy rats
(Pergamon-Elsevier Science Ltd, 2022)
Objective: Basal ganglia structures play an important role in the pathophysiology of absence epilepsy, known as remote control of absence seizures. We examined the role of the nigrostriatal dopaminergic pathway in absence ...