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Levetiracetam attenuates rotenone-induced toxicity: A rat model of Parkinson's disease.
(Elsevier, 2016)
Levetiracetam (LEV), a second-generation anti-epileptic drug, is used for treatment of both focal and generalized epilepsy. Growing body of evidence suggests that LEV may have neuroprotective effects. The present study was ...
Oxidative stress and cannabinoid receptor expression in type-2 diabetic rat pancreas following treatment with Δ9-THC
(Wiley Pub., 2014)
The objectives of study were (a) to determine alteration of feeding, glucose level and oxidative stress and (b) to investigate expression and localization of cannabinoid receptors in type-2 diabetic rat pancreas treated ...
Montelukast inhibits pentylenetetrazol-induced seizures in rats.
(Medical Science International, 2015)
Background: Montelukast is an antiinflammatory drug with an antioxidant property. In this study, we aimed to reveal whether montelukast has a preventive effect against seizures and post-seizure oxidative stress in ...
The cooperative effect of local angiotensin-II in liver with adriamycin hepatotoxicity on mitochondria.
(Medical Science International Publishing, 2016)
Background: Adriamycin (ADR) is a drug used clinically for anticancer treatment; however, it causes adverse effects in the liver. The mechanism by which these adverse effects occur remains unclear, impeding efforts to ...
Protective effect of edaravone against manganese-induced toxicity in cultured rat astrocytes.
(Elsevier, 2015)
Manganese (Mn), a trace metal, is essential for maintaining the normal regulation of many biochemical and cellular processes. However, accumulation of Mn due to excessive environmental exposure leads to neurological ...
Oxidative stress in children with chronic spontaneous urticaria
(Hindawi Publishing Corporation, 2016)
The pathogenesis of chronic spontaneous urticaria (CSU) has not been fully understood; nevertheless, significant progress has been achieved in recent years. The aim of this study was to investigate the possible role of ...