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The role of mediastinal adipose tissue 11 beta-hydroxysteroid d ehydrogenase type 1 and glucocorticoid expression in the development of coronary atherosclerosis in obese patients with ischemic heart disease
(BMC, 2012)
Background: Visceral fat deposition and its associated atherogenic complications are mediated by glucocorticoids. Cardiac visceral fat comprises mediastinal adipose tissue (MAT) and epicardial adipose tissue (EAT), and MAT ...
Effects of the Prenatal Administration of Tetanus Toxoid on the Sociability and Explorative Behaviors of Rat Offspring: A Preliminary Study
(Korean Coll Neuropsychopharmacology, 2021)
Objective: Autism spectrum disorder (ASD) is a severely disabling psychiatric disease characterized by impairments in communication and social skills. Although efforts have been made to explore the etiology of ASD, its ...
Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model
(Acta Cirurgica Brasileira, 2022)
Purpose: To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats. Methods: Thirty male Wistar albino rats were used. Rats were randomly divided into three equal groups, and ...
Radiotherapy and high bilirubin may be metformin like effect on lung cancer via possible AMPK pathway modulation
(Aepress Sro, 2022)
PURPOSE: L ife expectancy of cancer patients determine the regimen of treatment. There is no feasible marker that determines the survival other than the stage of the disease or other patients related factors. Bilirubin can ...
Are elevated mitochondrial DNA fragments in prostatic inflammation a potential biomarker for prostate cancer?
(Pagepress Publ, 2023)
Background: We sought to determine whether two soluble forms with different size of mtDNA are linked to prostatic inflammation, and whether they discriminate prostate cancer (PCa) from inflammatory prostatic conditions.Methods: ...