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Toplam kayıt 13, listelenen: 1-10
EVALUATION OF OXIDATIVE STRESS IN EXPERIMENTAL ACETAMINOPHEN INDUCED HEPATOTOXICITY: EFFECTS OF DARBEPOETIN ADMINISTRATION
(NOBEL ILAC, 2010)
Objective Effects of darbepoetin alfa on acetaminophen induced hepatotoxicity have been investigated by evaluating some oxidant/antioxidant parameters and liver histology Material and Method Fifty adult male Sprague Dawley ...
Levetiracetam attenuates rotenone-induced toxicity: A rat model of Parkinson's disease.
(Elsevier, 2016)
Levetiracetam (LEV), a second-generation anti-epileptic drug, is used for treatment of both focal and generalized epilepsy. Growing body of evidence suggests that LEV may have neuroprotective effects. The present study was ...
Oxidative stress and cannabinoid receptor expression in type-2 diabetic rat pancreas following treatment with Δ9-THC
(Wiley Pub., 2014)
The objectives of study were (a) to determine alteration of feeding, glucose level and oxidative stress and (b) to investigate expression and localization of cannabinoid receptors in type-2 diabetic rat pancreas treated ...
Montelukast inhibits pentylenetetrazol-induced seizures in rats.
(Medical Science International, 2015)
Background: Montelukast is an antiinflammatory drug with an antioxidant property. In this study, we aimed to reveal whether montelukast has a preventive effect against seizures and post-seizure oxidative stress in ...
The cooperative effect of local angiotensin-II in liver with adriamycin hepatotoxicity on mitochondria.
(Medical Science International Publishing, 2016)
Background: Adriamycin (ADR) is a drug used clinically for anticancer treatment; however, it causes adverse effects in the liver. The mechanism by which these adverse effects occur remains unclear, impeding efforts to ...
The antioxidant and antiapoptotic effect of boric acid on hepatoxicity in chronic alcohol-fed rats
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2018)
The harmful use of alcohol is a worldwide problem involving all ages. This study aims to investigate chronic alcohol exposure related hepatotoxicity on the rat liver and possible hepatoprotective effects of boric acid. ...
Protective effect of edaravone against manganese-induced toxicity in cultured rat astrocytes.
(Elsevier, 2015)
Manganese (Mn), a trace metal, is essential for maintaining the normal regulation of many biochemical and cellular processes. However, accumulation of Mn due to excessive environmental exposure leads to neurological ...
Oxidative stress in children with chronic spontaneous urticaria
(Hindawi Publishing Corporation, 2016)
The pathogenesis of chronic spontaneous urticaria (CSU) has not been fully understood; nevertheless, significant progress has been achieved in recent years. The aim of this study was to investigate the possible role of ...
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study
(WILEY, 2018)
The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group ...
Effects of lycopene on oxidative stress and remnant liver histology after partial hepatectomy in rats
(TURKISH SOC GASTROENTEROLOGY, 2011)
Background/aims: Partial hepatectomy is performed for the treatment of mass lesions in the liver. Lycopene, which is a carotenoid, is present in various physiologic processes. In this study, the effects of lycopene ...