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Toplam kayıt 104, listelenen: 11-20
Highly selective SGLT2 inhibitor dapagliflozin reduces seizure activity in pentylenetetrazol-induced murine model of epilepsy
(BIOMED CENTRAL LTD, 2018)
Background: Worldwide, over 10 million individuals suffer from drug-resistant epilepsy. New therapeutic strategies are needed to address this debilitating disease. Inhibition of sodium-glucose linked transporters (SGLTs), ...
A SOD2 Polymorphism is Associated with Abnormal Quantitative Sensory Testing in Type 2 Diabetic Patients
(AVES, 2018)
Introduction: Diabetes mellitus (DM) affects peripheral nerves inducing diabetic polyneuropathy (DPN). Mitochondria! dysfunction and oxidative stress are potential causes of DPN. Methods: Nerve conduction studies were ...
Analysis of genetic polymorphisms associated with intervertebral disc degeneration
(C M B ASSOC, 2018)
Intervertebral disc degeneration (IVDD) is a common degenerative spinal condition. Recent studies have shown that the incidence of disc herniation and disc degeneration may be explained by genetic factors. In this study, ...
Preoperative Lymphedema-Related Risk Factors in Early-Stage Breast Cancer
(MARY ANN LIEBERT, INC, 2018)
Background: Prolongation of survival in patients with breast cancer due to early diagnosis and modern methods of treatment has turned the attention on lymphedema, which is the most important morbidity secondary to the ...
Can serum soluble urokinase plasminogen activator receptor be an effective marker in the diagnosis of appendicitis and differentiation of complicated cases?
(TURKISH ASSOC TRAUMA EMERGENCY SURGERY, 2018)
BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is a new biomarker of inflammation level. The aim of the study was to evaluate whether suPAR levels could be useful to detect acute appendicitis and to ...
Possible role of stress, coping strategies, and life style in the development of breast cancer
(SAGE PUBLICATIONS INC, 2018)
Objective The aim of the present study was to investigate the possibility of the effect of life long stressful events, along with coping method used, perception of social support, and life style on the development of breast ...
Dipeptidyl peptidase-4 inhibition prevents cell death via extrinsic and intrinsic apoptotic pathways in rat pancreas with insulin resistance
(WILEY, 2018)
The study aims to evaluate the effect of saxagliptin, a specific inhibitor of dipeptidyl peptidase-4 enzymes, on body weight gain, lipid profiles, and cell death through apoptosis in rats with insulin resistance (IR). Male ...
Pulmonary hypertension experience in an expert university hospital
(TURKISH SOC CARDIOLOGY, 2018)
Objective: Pulmonary artery hypertension (PAH) is characterized by remodeling of the small pulmonary arteries, leading to a progressive increase in pulmonary vascular resistance and right ventricular failure. In this study, ...
Effect of gestational diabetes mellitus on testis and pancreatic tissues of male offspring
(WILEY, 2018)
The purpose of this study was to determine the effect of gestational diabetes mellitus (GDM) on some reproductive characteristics, testicular and pancreatic oxidative status and pancreatic endocrine receptor densities of ...
Glycoprotein Ib alpha Kozak polymorphism in patients presenting with early-onset acute coronary syndrome
(TERMEDIA PUBLISHING HOUSE LTD, 2018)
Introduction: Glycoprotein Ib alpha (GPIb alpha) receptor is the chief molecule responsible for initial platelet adhesion to the subendothelium. A thymidine to cytosine single nucleotide substitution at position -5 from ...