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Toplam kayıt 15, listelenen: 1-10
EVALUATION OF OXIDATIVE STRESS IN EXPERIMENTAL ACETAMINOPHEN INDUCED HEPATOTOXICITY: EFFECTS OF DARBEPOETIN ADMINISTRATION
(NOBEL ILAC, 2010)
Objective Effects of darbepoetin alfa on acetaminophen induced hepatotoxicity have been investigated by evaluating some oxidant/antioxidant parameters and liver histology Material and Method Fifty adult male Sprague Dawley ...
Exenatide, a GLP-1 analog, has healing effects on LPS-induced autism model: Inflammation, oxidative stress, gliosis, cerebral GABA, and serotonin interactions
(Wiley, 2020)
Previous studies have established anti-inflammatory, antioxidant, and neuroprotective effects of Exenatide in the central nervous system. Since these mechanisms are thought to have important roles in the pathophysiology ...
Investigation of the protective effects of boric acid on ethanol induced kidney injury
(Taylor & Francis Ltd, 2020)
Boric acid (BA) is used as an antioxidant and anti-inflammatory agent, and for regulating mitochondrial membrane potential in many disorders. We investigated the protective effects of BA against chronic ethanol toxicity ...
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study
(WILEY, 2018)
The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group ...
Effect of dietary curcumin and capsaicin on testicular and hepatic oxidant-antioxidant status in rats fed a high-fat diet
(CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS, 2019)
This study investigated the effects of curcumin and capsaicin on testicular and hepatic oxidant-antioxidant status in rats fed a high-fat diet (HFD). Male Sprague-Dawley rats were divided into 5 groups (8 rats per group). ...
Age-related changes in the activity and expression of manganese superoxide dismutase, and mitochondrial oxidant generation in female and male rats
(TURKISH BIOCHEM SOC, 2013)
Objective: The aim of this study was to examine the age-and gender-related differences in peroxide production, manganese superoxide dismutase (MnSOD) activity and expression in liver mitochondria of Wistar rats at 12 and ...
Hexagonal boron nitride nanoparticles trigger oxidative stress by modulating thiol/disulfide homeostasis
(Sage Publications Ltd, 2021)
Background: Hexagonal boron nitride nanoparticles (hBN NPs) are encouraging nanomaterials with unique chemical properties in medicine and biomedical fields. Until now, the optimal hBN NP's dosage and biochemical mechanism ...
Oxidative stress and inflammatory response of ghrelin on myocardial and aortic tissues in insulin-resistant rats
(Wiley, 2021)
Objectives This study was designed to clarify the effects of ghrelin on myocardial and aortic tissues in insulin-resistant rats. Methods Sprague-Dawley rats were divided into the following groups: control (Group 1), insulin ...
Effect of fulvic acid on gastric mucosa damage caused by chronic water avoidance stress
(Taylor & Francis Ltd, 2021)
We investigated the antioxidant and anti-ulcerogenic effects of fulvic acid (FA) on oxidative damage caused by water avoidance stress (WAS) in rat gastrointestinal mucosa. Three experimental groups were established: control ...
Papaverine Has Therapeutic Potential for Sepsis-Induced Neuropathy in Rats, Possibly via the Modulation of HMGB1-RAGE Axis and Its Antioxidant Prosperities
(Taylor and Francis Ltd., 2022)
Aim: Our aim was to investigate the possible neuroprotective properties of papaverine in sepsis-induced critical illness neuropathy (SCIN) through the evaluation of various inflammatory biochemical markers, including ...