Ara
Toplam kayıt 29, listelenen: 1-10
Effects of crataegus microphylla on vascular dysfunction in streptozotocin-induced diabetic rats
(2013)
Vascular dysfunction plays a key role in the pathogenesis of diabetic vascular disease. In this study, we aimed to investigate whether chronic in vivo treatment of Crataegus microphylla (CM) extract in diabetic rats induced ...
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study
(WILEY, 2018)
The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group ...
Octreotide protects ovary against ischemia-reperfusion injury in rats: Evaluation of histological and biochemical parameters
(WILEY-BLACKWELL, 2015)
AimThis study investigated the efficacy of octreotide for prevention of ischemia-reperfusion injury in rat ovary. MethodsThirty-two adult female rats were included. Rats were divided into five groups: in the sham group, ...
Delta(9)-tetrahydrocannabinol treatment improved endothelium-dependent relaxation on streptozotocin/nicotinamide-induced diabetic rat aorta
(AKADEMIAI KIADO RT, 2015)
Objective: In this study, we investigated the possible effect of Delta(9)-tetrahydrocannabinol (THC), a peroxisome proliferator-activated receptor gamma (PPAR.) agonist, on metabolic control and vascular complications of ...
Hexagonal boron nitride nanoparticles trigger oxidative stress by modulating thiol/disulfide homeostasis
(Sage Publications Ltd, 2021)
Background: Hexagonal boron nitride nanoparticles (hBN NPs) are encouraging nanomaterials with unique chemical properties in medicine and biomedical fields. Until now, the optimal hBN NP's dosage and biochemical mechanism ...
Effect of chronic alcohol consumption on myocardial apoptosis in the rat model of isoproterenol-induced myocardial injury and investigation on the cardioprotective role of calpain inhibitor 1
(Taylor & Francis Ltd, 2021)
We investigated the presence of myocardial apoptosis on isoproterenol (ISO)-induced myocardial injury (MI) after long-term high dose alcohol consumption and examined the antiapoptotic role of calpain inhibitor 1. Male ...
Oktreotidin, sepsis modelinde sıçanların akciğerleri üzerindeki kısa dönem koruyucu etkisi
(NLM (Medline), 2022)
BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ...
Anti-seizure effect of zinc on PTZ-induced epilepsy in rat model
(Comenius University in Bratislava, 2022)
Epilepsy is a widespread and mainly severe neurological condition portrayed by recurring spontaneous seizures caused by the brain’s abnormal electrical activity. According to new research, infl ammation may be both a result ...
Mesenchymal stem cells have ameliorative effect on the colitis model via Nrf2/HO-1 pathway
(Sociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia, 2022)
Purpose: To evaluate the ameliorative effect of mesenchymal stem cells (MSCs) on acetic acid colitis model via Nrf2/HO-1 pathway in rats. Methods: In this study, 30 rats were divided into three groups. Acute colitis was ...
Papaverine Has Therapeutic Potential for Sepsis-Induced Neuropathy in Rats, Possibly via the Modulation of HMGB1-RAGE Axis and Its Antioxidant Prosperities
(Taylor and Francis Ltd., 2022)
Aim: Our aim was to investigate the possible neuroprotective properties of papaverine in sepsis-induced critical illness neuropathy (SCIN) through the evaluation of various inflammatory biochemical markers, including ...