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Toplam kayıt 14, listelenen: 1-10
A plant oxylipin, 12-oxo-phytodienoic acid, inhibits proliferation of human breast cancer cells by targeting cyclin D1
(2008)
Cyclin D1 overexpression has been associated with poor prognosis and resistance to therapy in human breast cancer. Thus, the development of therapeutic agents that selectively target cyclin D1 activity is of clinical ...
Predictive and prognostic significance of p27, Akt, PTEN and PI3K expression in HER2-positive metastatic breast cancer
(Asian Pacific Organization for Cancer Prevention, 2015)
Background: The phosphatidylinositol 3'-kinase/Akt (PI3K/Akt) pathway is a key regulator for HER2-overexpressing breast cancer, but data about whether activation of PI3K/Akt is associated with poor prognosis and resistance ...
Angiogenesis inhibition in breast cancer
(Springer International Publishing, 2016)
Angiogenesis plays an essential role in tumor development, invasion, and metastasis. In preclinical models, agents that block the vascular endothelial growth factor (VEGF) pathway have been shown to effectively inhibit ...
JNK pathway regulates estradiol-induced apoptosis in hormone-dependent human breast cancer cells
(2007)
Estrogen is known to stimulate breast cancer development in humans. Ironically, high doses of estrogen can induce regression of hormone-dependent breast cancer in postmenopausal women. The mechanism by which estrogen induces ...
Long extensive transverse myelitis associated with aquaporin-4 antibody and breast cancer: Favorable response to cancer treatment
(MANEY PUBLISHING, 2012)
Context: Long extensive transverse myelitis (LETM) seldom develops in patients with breast cancer who are aquaporin-4 antibody (Aqp-4 Ab)-positive. Whether this association is coincidental is not well understood. Findings: ...
Determining the Awareness of and Compliance with Breast Cancer Screening among Turkish Residential Women
(ASIAN PACIFIC ORGANIZATION CANCER PREVENTION, 2013)
Background: Breast cancer is the leading cause of cancer-related deaths in women. Despite being associated with high morbidity and mortality, breast cancer is a disease that can be diagnosed and treated early. Materials ...
Interobserver reproducibility of tumor-infiltrating lymphocyte evaluations in breast cancer
(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2018)
Aim: Tumor-infiltrating lymphocytes (TILs) have a prognostic value in breast cancer (BC); however, because of the lack of standard evaluation methods, we aimed to assess the interobserver agreement of stromal TILs (sTILs) ...
The quality of life and self-efficacy of Turkish breast cancer patients undergoing chemotherapy
(ELSEVIER SCI LTD, 2008)
Self-efficacy has a positive effect on health behaviors, symptom control, compliance with cancer treatment, and quality of life. This study aims to describe the quality of life and self-efficacy of Turkish breast cancer ...
MANAGEMENT OF ADENOID CYSTIC CARCINOMA OF THE BREAST: A RARE CANCER NETWORK STUDY
(ELSEVIER SCIENCE INC, 2012)
Background: Mammary adenoid cystic carcinoma (ACC) is a rare breast cancer. The aim of this retrospective study was to assess prognostic factors and patterns of failure, as well as the role of radiation therapy (RT), in ...
The investigation of the changes in the surface glycoconjugates using two different spheroid models of breast cancer cells and availability assessment of these spheroid models for rapid diagnosis
(Ondokuz Mayis Universitesi, 2021)
The importance of early cancer diagnosis has led to development of many different diagnostic methods. In this context, the studies investigating the presence and amount of sugar residues to use as indicators in the ...