Ara
Toplam kayıt 18, listelenen: 1-10
The reducing effect of agomelatine on pentylenetetrazol-induced convulsions
(Akademiai Kiado Zrt, 2019)
Introduction: Agomelatine is a potent MT1 and MT2 melatonin receptor agonist and a 5-HT2C serotonin receptor antagonist. the purpose of this study was to show the convulsion-reducing effect of agomelatine, in both clinical ...
The efficacy of Aesculus hippocastanum seeds on diabetic nephropathy in a streptozotocin-induced diabetic rat model
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2016)
Cytokines, such as transforming growth factor (TGF)-beta 1, and increased oxidative stress are considered to be responsible for the development of diabetic nephropathy. We hypothesized that Aesculus hippocastanum (AH) seeds ...
The Effects of Lipid Emulsion, Magnesium Sulphate and Metoprolol in Amitriptyline-Induced Cardiovascular Toxicity in Rats
(HUMANA PRESS INC, 2018)
The aim of this study was to evaluate the effects of metoprolol, lipid emulsion and MgSO4 which can be recommended for prevention of long QT that is one of the lethal consequences of amitriptyline intoxication. Thirty ...
Inhibitor effect of paricalcitol in rat model of pentylenetetrazol-induced seizures
(SPRINGER, 2016)
Vitamin D has various systemic effects on bone metabolism, modulation of the immune system, stabilization of the cell membrane, oxidative stress, inflammation, apoptosis, and various other hormones. Differing from active ...
Evaluation of long-term effects of artificial sweeteners on rat brain: a biochemical, behavioral, and histological study
(WILEY, 2018)
The aim of the present study was to compare the effects of artificial sweeteners (aspartame, saccharin, and sucralose) on rat brain. Twenty-four adult male Sprague-Dawley rats were included in the study. The control group ...
Protection by Edaravone, a Radical Scavenger, against Manganese-Induced Neurotoxicity in Rats
(WILEY-BLACKWELL, 2016)
Manganese (Mn) is a required element for biological systems; however, its excessive exposure may lead to a neurological syndrome known as manganism. The aim of the present study was to assess the toxic effects of subacute ...
Therapeutic effect of sunitinib on diabetes mellitus related ovarian injury: an experimental rat model study
(INFORMA HEALTHCARE, 2015)
The aim of our study is to investigate the effect of sunitinib on diabetes mellitus related-ovarian injury and fibrosis in rat models. An experimental diabetes mellitus model was created in 16 rats, and eight rats with ...
Neurobehavioral effects of long-term maternal fructose intake in rat offspring
(PERGAMON-ELSEVIER SCIENCE LTD, 2018)
Background: Previous studies have indicated an association between maternal metabolic conditions and general developmental disturbances of the offspring. Objective: We aimed to investigate the influence of long-term maternal ...
Octreotide protects ovary against ischemia-reperfusion injury in rats: Evaluation of histological and biochemical parameters
(WILEY-BLACKWELL, 2015)
AimThis study investigated the efficacy of octreotide for prevention of ischemia-reperfusion injury in rat ovary. MethodsThirty-two adult female rats were included. Rats were divided into five groups: in the sham group, ...
The effects of diltiazem and metoprolol in QTc prolongation due to amitriptyline intoxication
(SAGE PUBLICATIONS LTD, 2016)
Background and objective: Amitriptyline, a frequently used tricyclic antidepressant agent, has powerful cardiotoxic effects especially in high doses. Serum and urine levels of amitriptyline dosages are not correlated with ...