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Toplam kayıt 7, listelenen: 1-7
Papaverine Has Therapeutic Potential for Sepsis-Induced Neuropathy in Rats, Possibly via the Modulation of HMGB1-RAGE Axis and Its Antioxidant Prosperities
(Taylor and Francis Ltd., 2022)
Aim: Our aim was to investigate the possible neuroprotective properties of papaverine in sepsis-induced critical illness neuropathy (SCIN) through the evaluation of various inflammatory biochemical markers, including ...
Preventive effect of trimetazidine against ischemia-reperfusion injury in rat epigastric island flaps: an experimental study
(Springer Science and Business Media Deutschland GmbH, 2021)
Background: For plastic surgery, ischemia-reperfusion (I-R) injury is a critical problem that results in partial or total flap necrosis. Trimetazidine (TMZ) is a drug used in the treatment of angina pectoris. This study ...
Evaluation of the Reparative Effect of Sinomenine in an Acetaminophen-Induced Liver Injury Model
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)
Due to its rising global prevalence, liver failure treatments are urgently needed. Sinomenine (SIN), an alkaloid from sinomenium acutum, is being studied for its liver-repair properties due to Acetaminophen (APAP) overdose. ...
Thiol/disulfide homeostasis and oxidant status in children with congenital heart disease
(De Gruyter Open Ltd, 2022)
Objectives: This article aims to explain the altered oxidative status and thiol/disulfide homeostasis before and after surgery in children with congenital heart disease (CHD). Methods: Blood samples were taken from the ...
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease
(Elsevier B.V., 2023)
Background: Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that primarily affects the motor system. Although there are several treatments available to alleviate PD symptoms, there is ...
Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology
(Turkish Association of Trauma and Emergency Surgery, 2023)
BACKGROUND: Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate ...
Adipose-derived mesenchymal stem cells mitigate methotrexate-induced liver cirrhosis (fibrosis) model
(Verduci Editore s.r.l, 2023)
OBJECTIVE: Hepatic fibrosis is a severe liver condition characterized by abnormal fibroblast activity, excessive extracellular matrix deposition, inflammation, and structural alterations. Methotrexate (MTX), a pharmaceutical ...