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Toplam kayıt 11, listelenen: 1-10
Delta(9)-tetrahydrocannabinol treatment improved endothelium-dependent relaxation on streptozotocin/nicotinamide-induced diabetic rat aorta
(AKADEMIAI KIADO RT, 2015)
Objective: In this study, we investigated the possible effect of Delta(9)-tetrahydrocannabinol (THC), a peroxisome proliferator-activated receptor gamma (PPAR.) agonist, on metabolic control and vascular complications of ...
Oktreotidin, sepsis modelinde sıçanların akciğerleri üzerindeki kısa dönem koruyucu etkisi
(NLM (Medline), 2022)
BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ...
Anti-seizure effect of zinc on PTZ-induced epilepsy in rat model
(Comenius University in Bratislava, 2022)
Epilepsy is a widespread and mainly severe neurological condition portrayed by recurring spontaneous seizures caused by the brain’s abnormal electrical activity. According to new research, infl ammation may be both a result ...
Mesenchymal stem cells have ameliorative effect on the colitis model via Nrf2/HO-1 pathway
(Sociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia, 2022)
Purpose: To evaluate the ameliorative effect of mesenchymal stem cells (MSCs) on acetic acid colitis model via Nrf2/HO-1 pathway in rats. Methods: In this study, 30 rats were divided into three groups. Acute colitis was ...
Vitamins C and E protect from sepsis-induced lung damage in rat and CT correlation
(Comenius University in Bratislava, 2022)
BACKGROUND: Sepsis is one of the leading causes of death in intensive care units worldwide. Vitamins C and E are natural antioxidants and anti-infl ammatory agents. Suppressing the infl ammation is an important treatment ...
Beneficial effects of sennoside B on pentylenetetrazole-induced seizures in rats
(SAGE Publications Ltd, 2023)
Background: Epilepsy is a common disorder affecting approximately 50 million people worldwide. Oxidative stress is known to play an important role in the pathophysiology of diseases, including epilepsy. In this study, we ...
Short-term protective effect of octreotide on the lungs of rats with experimentally induced sepsis
(Turkish Association of Trauma and Emergency Surgery, 2022)
BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ...
Evaluation of the Reparative Effect of Sinomenine in an Acetaminophen-Induced Liver Injury Model
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)
Due to its rising global prevalence, liver failure treatments are urgently needed. Sinomenine (SIN), an alkaloid from sinomenium acutum, is being studied for its liver-repair properties due to Acetaminophen (APAP) overdose. ...
The Effect of Liraglutide on Axon Regeneration and Functional Recovery after Peripheral Nerve Lesion
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)
Peripheral nerve injuries inflict severe consequences, necessitating innovative therapeutic strategies. This study investigates the potential of liraglutide, a glucagon-like peptide-1 receptor agonist, in mitigating the ...
Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology
(Turkish Association of Trauma and Emergency Surgery, 2023)
BACKGROUND: Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate ...