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Toplam kayıt 1686, listelenen: 1651-1660
Immunosuppressant Tacrolimus Treatment Delays Acute Seizure Occurrence, Reduces Elevated Oxidative Stress, and Reverses PGF2? Burst in the Brain of PTZ-Treated Rats
(Springer/Plenum Publishers, 2023)
It is still an urgent need to find alternative and effective therapies to combat epileptic seizures. Tacrolimus as a potent immunosuppressant and calcineurin inhibitor is emerging as promising drug to suppress seizures. ...
Investigation of the effectiveness of teledermatology in the diagnosis of skin lesions in pediatric patients
(Assoc Medica Brasileira, 2023)
OBJECTIVE: Teledermatology is the use of communications technology to enable the remote evaluation of skin lesions. Dermatological complaints are common among pediatric patients and should be handled differently than adults. ...
COSMC expression as a predictor of remission in IgA nephropathy
(Springer Science and Business Media B.V., 2023)
Purpose: The impact of core 1,3-galactosyltransferase-specific molecular chaperon (COSMC) gene expression and methylation profile on clinical progression of IgA nephropathy (IgAN) is unclear. The aim of this study was to ...
Ductal prostate cancer: Clinical features and outcomes from a multicenter retrospective analysis and overview of the current literature
(Lippincott Williams & Wilkins, 2022)
Objective The aim of the study is to evaluate clinical features and outcomes after different therapeutic strategies for ductal prostate adenocarcinoma (DPC), a rare but aggressive subtype of invasive prostate cancer (PCa) ...
Higher rates of cefiderocol resistance among NDM producing Klebsiella bloodstream isolates applying EUCAST over CLSI breakpoints
(Taylor & Francis Ltd, 2023)
BackgroundCefiderocol is generally active against carbapenem-resistant Klebsiella spp. (CRK) with higher MICs against metallo-beta-lactamase producers. There is a variation in cefiderocol interpretive criteria determined ...
Short term protective effect of digitoxin in sepsis-induced acute lung injury
(Tech Science Press, 2022)
Purpose: Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known antiinflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light ...
The Role of Neurosurgery in Global Health Cerebrovascular Surgery
(Springer International Publishing, 2022)
Cerebrovascular diseases (CD) are a global health problem. CD are the second cause of death in developed countries, the first cause of disability in adults, and the second cause of dementia. Although neurosurgical development ...
Adipose-derived mesenchymal stem cells mitigate methotrexate-induced liver cirrhosis (fibrosis) model
(Verduci Editore s.r.l, 2023)
OBJECTIVE: Hepatic fibrosis is a severe liver condition characterized by abnormal fibroblast activity, excessive extracellular matrix deposition, inflammation, and structural alterations. Methotrexate (MTX), a pharmaceutical ...
Investigation of Neuroprotective Effect of Shilajit Extract in Experimental Head Trauma Model Created in Rats
(Turkish Neurosurgical Society, 2023)
AIM: To investigate the neuroprotective effect of shilajit extract in experimental head trauma. MATERIAL and METHODS: Three groups of 33 Sprague Dawley Albino strain male rats were included in the study. Group 1 (n=11): ...
Total Antioxidant Potential, Total Phenolic Profile and Cytotoxic Activity Against Brain Cancer: Melocan and Galdirik
(University of Zagreb, 2023)
Research background. Brain cancer is known to be one of the most difficult types of cancer to cure. It has a serious impact on the lives of diagnosed people due to the insufficient treatment options and their side effects. ...