Ara
Toplam kayıt 28, listelenen: 21-28
Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model
(Acta Cirurgica Brasileira, 2022)
Purpose: To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats. Methods: Thirty male Wistar albino rats were used. Rats were randomly divided into three equal groups, and ...
Autophagy and anti-inflammation ameliorate diabetic neuropathy with Rilmenidine
(Acta Cirurgica Brasileira, 2023)
Purpose: To evaluate the neuroprotective effects of Rilmenidine on diabetic peripheral neuropathy (DPN) in a rat model of diabetes induced by streptozotocin (STZ). Methods: STZ (60 mg/kg) was administered to adult ...
The Effect of Adipose-Derived Mesenchymal Stem Cells on Peripheral Nerve Damage in a Rodent Model
(Mdpi, 2023)
Peripheral nerve damage is a significant clinical problem with limited therapeutic options. Adipose-derived mesenchymal stem cells (ADSCs) have emerged as a promising therapeutic approach due to their regenerative potential. ...
Effects of vitrification solution supplemented with platelet-rich plasma in rat ovarian tissue cryopreservation
(Tubitak Scientific & Technological Research Council Turkey, 2023)
Background/aim: The subject of this study was to investigate the utility of platelet-rich plasma (PRP) in the cryopreservation process to reduce cryodamage and increase tissue viability.Materials and methods: Twenty-one ...
Demonstration of the protective effect of propofol in rat model of cisplatin-induced neuropathy
(Aepress Sro, 2023)
Cisplatin is commonly used in the treatment of lung, genitourinary, and gastrointestinal cancers. Peripheral neuropathy is the most important side effect, leading to a decrease in the dose of cisplatin or its complete ...
N-acetyl cysteine: A new look at its effect on PTZ-induced convulsions
(Elsevier, 2023)
Introduction/Aim: Epilepsy is widely investigated as a common neurological disease requiring pharmacologically effective agents. N-acetyl cysteine (NAC), has become a remarkable molecule with its role in both antioxidant ...
Prenatal Exposure to COVID-19 mRNA Vaccine BNT162b2 Induces Autism-Like Behaviors in Male Neonatal Rats: Insights into WNT and BDNF Signaling Perturbations
(Springer/Plenum Publishers, 2024)
The COVID-19 pandemic catalyzed the swift development and distribution of mRNA vaccines, including BNT162b2, to address the disease. Concerns have arisen about the potential neurodevelopmental implications of these vaccines, ...
Short term protective effect of digitoxin in sepsis-induced acute lung injury
(Tech Science Press, 2022)
Purpose: Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known antiinflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light ...